Centre National De La Recherche Scientifique

Université´ D'aix-Marseille

UniversitÉ Libre De Bruxelles

Universite Aix-marseille

Centre National De La Recherche Scientifique-cnrs

Jérôme Charles Wenger

Hervé Rigneault

Gilles Van Assche

Thomas W Ebbesen

Nicolas Cerf

Philippe Grangier

Pierre Dominique Bon

Rosa Brouri-Tualle

Frédéric Grosshans

Pierre-François Lenne

Serge Olivier Pierre Monneret

Evgueni Popov

A method for detecting the presence of an analyte () in a solution () comprising: providing at least a first and a second probes (A, B) different from each other, each probe (A,B) comprising a nanoparticle conjugated with a receptor specific to the analyte (); contacting the solution () suspected of including the analyte () with the first and the second probes (A, B) to form a sample solution (), wherein the sample solution () comprises aggregates () comprising the analyte () combined with the first and the second probes (A, B); illuminating the sample solution () with a light source having at least a first and a second exciting wavelengths (&#x3bb;, &#x3bb;) different from each other wherein the first and the second wavelength are chosen to get specific optical responses from the first probe (A) and the second probe (B) respectively when illuminated; detecting as a function of time the light scattered by the first probe (A) at a first detection wavelength (&#x3bb;) and the light scattered by the second probe (B) at a second detection wavelength (&#x3bb;) to get a first signal and a second signal respectively; and detecting temporal coincidences between said first signal and second signal.

Detection of analytes using nanoparticles as light scattering enhancers

The invention relates to a device (II) for three-dimensional focusing in a microscope (I) with a given resolution, comprising: &#x2014;a detector () making it possible to determine, in a given measuring plane, a phase and intensity image of an electromagnetic field resulting from the interaction of an incident light wave with a reference object () situated in a reference medium with a given index and having a complex refractive index, the real part and/or the imaginary part of which differs from the real part and/or the imaginary part, respectively, of the refractive index of the reference medium; &#x2014;computation means () making it possible to determine a three-dimensional position variation of the reference object () from at least one phase and intensity image.

Three-dimensional focusing device and method for a microscope

The invention relates to a device () for detecting the emission of a target particle () at an emission wavelength, said device comprising: a photo-detector (A,B) comprising a sensitive detection surface having a high optical index; wherein said target particle () can be positioned in the vicinity of said sensitive surface in an analysis medium () having a low optical index; said device being characterized in that it further comprises: a mask () covering said sensitive surface, said mask including at least one area () opaque at said emission wavelength and at least one hole (), said hole being capable of receiving the target particle; and in that the mask includes at least one interface;said device further comprising at least one groove (A,B) provided at said interface, each of said at least one groove surrounding each of said at least one hole.

Device for the exalted detection of the emission of a target particle

One aspect of the present invention is related to a quantum cryptographic scheme comprising at least one sending unit including a physical means of encoding and distributing a raw key in the quadrature components of quantum coherent states that are continuously modulated in phase and amplitude, at least one receiving unit containing a physical means of performing homodyne detection of the quantum coherent states in order to measure the quadrature components of the states, a quantum channel for connecting the sending unit to the receiving unit, a two-way authenticated public channel for transmitting non-secret messages between the sending unit and the receiving unit, a quantum key distribution protocol ensuring that the information tapped by a potential eavesdropper can be estimated from the quantum channel parameters, and a direct or reverse reconciliation protocol that converts the raw continuous data into a common binary key.

High-rate quantum key distribution scheme relying on continuously phase and amplitude-modulated coherent light pulses

Growing community of inventors

Vitrolles, France

Jérôme Charles Wenger