Richter Gedeon Vegyeszeti Gyar Rt

Richter Gedeon Nyrt.

János Fischer

Krisztina Vukics

Endréne Petényi

Tamás Róbert Trischler, Legal Representative

János Leibinger

Sándor Lévai

György Szabo

Gabriel Maria Trischler, Legal Representative

Tamás Fodor

Katalin Szöke

Istvánné Kis-Varga

Ferenc Trischler, Jr, Legal Representative

Andrea Donát

Péter Erdelyi

Krisztina Lanczos

Sándorné Balint

Sándor Levai

Mónika Vastag

Béla Hegedüs

Károly Tihanyi

Attila Szemzö

The present invention relates to new compounds of formula (I), (I) wherein the meaning of Ris hydrogen atom, C-Cacyl group, benzoyl group or R&#x2014;COORgroup, Y is hydrogen atom or alkali ion, Ris C-Cstraight or branched alkylidene group and Ris hydrogen atom, C-Calkyl group or alkali ion, and/or stereoisomers and/or diastereomers and/or pharmaceutically acceptable salts and/or hydrates and/or solvates thereof, which are suitable for the treatment of pain of acute and chronic inflammation origin as well as postoperative pain and dysmenorrhea. The invention also relates to the process of the synthesis of compounds of formula (I) as well as the pharmaceutical composition containing the same and the use for treatment of pain, inflammation and disorders associated with inflammation.

1, 2-diaryl pyrazoles useful as analgetic and antiinflammatory agents

The object of the present invention are new desloratadine salts of formula I wherein the meaning of X is an acid residue and the meaning of n is 1 or 2, and formula II wherein the meaning of X is a pK &#x3c;3.5 acid residue. The invention is related to a process for their synthesis, as well as new anti-allergic pharmaceutical compositions containing these salts 

Desloratadine salts, process for their synthesis and pharmaceutical compositions thereof

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Budapest, Hungary

János Fischer