Danisco A/s

International N&h Denmark Aps

Dupont Nutrition Biosciences Aps

Jyrki Airaksinen

Kari Laiho

Heikki Heikkilä

Jari Lewandowski

Päivi Sarmala

Heikki HeikkilÄ

The present invention relates to a method for fractionating a feedstock into two or more fractions enriched with different components, and more particularly to a method for fractionating a feedstock into two or more fractions by a chromatographic sequential simulated moving bed (SMB) system, wherein the SMB system comprises a separation loop comprising at least 2 compartments; and wherein the method comprises a separation cycle comprising at least one feeding step, at least one circulating step and at least one eluting step; wherein the dissolved substances in the feedstock form a separation profile as they progress through the separation loop; and the separation profile is progressed more than once or less than once through the separation loop in each separation cycle; and wherein at least two flow paths are present in the separation loop during each feeding step of the separation cycle; and at least one of said flow paths is an active flow path and at least one of said flow paths is an inactive flow path.

Chromatographic sequential simulated moving bed fractionation of a feedstock

The present invention relates to a chromatographic separation process for fractionating betaine-containing solutions by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The process provides improved separation capacity and separation efficiency without affecting the yield or purity of betaine or other products. The process can especially be applied to sequential SMB separation systems.

Separation process

The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems.

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Espoo, Finland

Jyrki Airaksinen