University of Rochester

Juvenal Ormachea Quispe

Kevin J Parker

Jose Fernando Zvietcovich Zegarra

Within the field of elastography, a new approach analyzes the limiting case of shear waves established as a reverberant field. In this framework, it is assumed that a distribution of shear waves exists, oriented across all directions in 3D (e.g. 2D space+time). The simultaneous multi-frequency application of reverberant shear wave fields can be accomplished by applying an array of external sources that can be excited by multiple frequencies within a bandwidth, for example 50, 100, 150, . . . 500 Hz, all contributing to the shear wave field produced in the liver or other target organ. This enables the analysis of the dispersion of shear wave speed as it increases with frequency, indicating the viscoelastic and lossy nature of the tissue under study. Furthermore, dispersion images can be created and displayed alongside the shear wave speed images. Studies on breast and liver tissues using the multi-frequency reverberant shear wave technique, employing frequencies up to 700 Hz in breast tissue, and robust reverberant patterns of shear waves across the entire liver and kidney in obese patients are reported. Dispersion images are shown to have contrast between tissue types and with quantitative values that align with previous studies.

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Rochester, NY, United States of America

Juvenal Ormachea Quispe