Wayne State University

Juri G Gelovani

Sonia S Hassan

Mohammad Mehrmohammadi

Yan Yan

Edgar Hernandez-Andrade

Aleksandr Shavrin

Philip Alther

Nashaat Turkman

Andrei Borisov

Vadim Popov

Robin Bonomi

Methods and system are described for multi-parametric, non-invasive, and real-time assessment of blood perfusion and oxygenation in the fetal brain during labor and delivery of a fetus through a vaginal birth canal of a maternal pelvis, and include positioning a probe device in the maternal pelvis during active labor, transmitting and receiving a plurality of ultrasound (US) and photoacoustic (PA) signals between the probe device and fetal brain, displaying in real-time on an US machine communicatively coupled to the probe device one or more images of venous and arterial blood flow of respective blood vessels in the fetal brain, measuring oxygen saturation of the respective venous and arterial blood vessels based on data from the one or more images, and estimating the oxygen measurement in the fetal brain during active labor based on the measured oxygen saturation.

Ultrasound and photoacoustic systems and methods for fetal brain assessment during delivery

Compositions and methods for detection and assessment of galectins are provided by the present invention, including labeled compositions, pharmaceutical composition including a labeled composition for galectin detection and a pharmaceutically acceptable carrier, method of aiding in diagnosis and/or treatment of a condition characterized by upregulation of one or more galectins in a subject in need thereof and precursor compositions for synthesis of chemical compositions, including but not limited to labeled compositions for detection and assessment of galectins.

Compositions and methods relating to galectin detection

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Detroit, MI, United States of America

Juri G Gelovani