Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Hoechst Aktiengesellschaft

Jurgen Logemann

Peter Eckes

Burkhard Sachse

Joachim Wink

Peter Braun

Jeff Schell

Heinz Hanel

John Mundy

Guido Jach

Jozef Schell

Rolf Hilgenfeld

Norbert Ulbrich

Birgit Gornhardt

Lothar Willmitzer

Ilan Chet

Josef Schell

The polypeptide with the sequence (SEQ ID NO:1) Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Al a-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cys can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent. Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.

Antifungal polypeptide and process for its production

Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).

Transgenic pathogen-resistant organism

Transgenic pathogen-resistant plant

Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.

Method of producing pathogen-resistant plants

The polypeptide with the sequence (SEQ ID NO: 1)

The invention relates to wound-stimulated DNA from Solanum tuberosum as well as parts thereof, their use for the development of gene products in higher plants using wounding or pathogen attack, DNA-transfer vectors containing these, and plants or plant portions containing these. The promoter of this DNA-sequence can be used for the expression of gene products in higher plants using wound and/or pathogen attack.

Wound-stimulated DNA-sequence from solanum tuberosum and its use

Growing community of inventors

Koln, Germany

Jurgen Logemann