Hoechst Aktiengesellschaft

Behringwerke Aktiengesellschaft

Jurgen Gross

Hugo Wilmes

Arno Holst

Helmut Lask

Axel Sieber

Hans D Sanger

Rudolf Kressirer

Reinhard Dinges

Rudiger Simonek

Holger Pufahl

Dieter Sanger

Karl-Heinz Schaller

Matthias Karger

In the photometer arrangement comprising a light source, lens system with beam splitter, measurement cell, scattered light trap and photodetector, said parts being arranged in this sequence, the scattered light trap comprises a honeycomb. The ratio between the free cross-section of its individual channels and the length thereof is from 1:40 to 1:300.

Photometer arrangement with scattered light trap

An incubation apparatus for microtiter plates includes an heating chamber and a incubation chamber. The heating chamber has a controllable hot air generator over which are arranged air guide devices for equalizing and distributing a stream of hot air to the microtiter plates. Air return devices are provided for collecting and returning hot air to the hot air generator. The heating chamber can be closed by a gate, and incubation chamber is divided by shelves into a plurality of compartments for receiving the microtiter plates. It is possible to close each compartment with a gate, and the side walls of the compartments are provided with heating devices. Furthermore, the incubation apparatus is provided with a gripping and transporting device having a working platform that is vertically displaceable and having a horizontally displaceable gripping arm.

Incubation device for microtiter plates

In the reaction vessel in the form of a cell for optical investigations of small quantities of liquid, the floor (4) of the reaction vessel exhibits a circular depression (6), in which a cylindrical body (9) is disposed so as to be moveable. The depression (6) exhibits arcuately extending channels (7), which extend from the depression (6) towards the walls (3) and/or the corners (8) of the reaction vessel.

Reaction vessel

In the apparatus for fixing the position of the test zones of a test strip and for reversing the latter, a guide (8) opens into a reversing device (1, 1a) for the test strips (2). Between the guide and the reversing device is arranged a closing means (9) for the guide, which is connected to a holding device (10) via a lever (5). The holding device (10) projects into the guide and is mounted rotatably in synchronism with the closing means (9). It is also equipped with a drive device (7). The reversing device has a moveable stop (4, 4a) which is driven by a position-detection means (3) arranged in the guide (8).

Apparatus for fixing the position of test zones of a test strip and for

An apparatus for transporting test material in strip form underneath a measuring device, the test material having various test zones along the length of the strip, the apparatus comprising conveyor means for transporting the test material; a retaining device disposed above the conveyor means at an angle transverse to the direction of movement of the conveyor means; and at least one heating device disposed on the retaining device for selectively heating individual test zones on the test material as the test material is transported by the conveyor means.

Apparatus for the transport of partially temperature-controlled test

In the device for evaluating test strips having individual test sections, which consist of a terminal, a work platform with holder for the test strips and a sensing head, a position mark 5 is arranged for each test section 9 on the side of the holder 13. On the work platform 15, the sensing head 14 is arranged so as to be capable of of traversing the test sections 9 and the position marks 5. The sensing head 14 is provided with light sources 6, which are directed towards the test sections 9, of different wavelength and with a light receiver and with at least one position detector 10 which is directed towards the position marks.

Device for evaluating test strips

A photometer head having a housing for receiving and supporting small test volumes. The housing includes a recess and a plate for substantially covering the recess. A light transmitter and a light receiver having first and second end surfaces are mounted within the housing and project into the recess at locations substantially opposite one another to define a gap between the first and second end surfaces for retaining the small test volumes. A liquid applicator extends through an aperture in the housing to dispense droplets of liquid test volumes into the gap. The light transmitter directs optical energy at the droplets and the light receiver receives the transmitted energy.

Photometer head for small test volumes

A cuvette for holding a liquid to be examined optically has front, back, and side walls defining a rectangular cross section and a Y-shaped structure at the bottom thereof for holding the liquid. The Y-shaped structure extends between transparent front and back walls with an upper funnel mouth extending to the side walls, and a liquid holding portion formed of inner walls spaced between the side walls, and extending down to a rounded, tub-shaped bottom. The front walls are transparent and serve also to form the front and back of the liquid holding portion. The bottom preferably has a frustroconic surface to minimize the amount of liquid required for examination and to facilitate mixing of liquids added to the cuvette. The side walls extend below the tub-shaped bottom, and are joined to the front and back wall midway up the liquid holding portion by means of a rib, so that light is not scattered by the side walls and optical inhomogeneities are prevented.

Cuvette with tub-shaped bottom for the optical examination of liquids

Antigen-antibody reactions are measured by passing laser light through the mixture of the antigen solution with the corresponding antibody and measuring the light scattered in the forward direction and determining its intensity. The device used comprises a measuring system consisting of a laser, at least two diaphragms, a system of lenses and a photodetector and a light trap having a diameter corresponding to 1.1 to 1.7 times the diameter of the laser beam.

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Hofheim am Taunus, Germany

Jurgen Gross