Sumitomo Pharma Co., Ltd.

Dainippon Sumitomo Pharma Co., Ltd.

Sumitomo Dainippon Pharma Co., Ltd.

Junya Ikeda

Yohei Ikuma

Andrew Simon Bell

Hidefumi Yoshinaga

Satoshi Adachi

Jeremy Besnard

Yoshinori Aihara

Harunobu Mitsunuma

Hiroyuki Nakahira

Hidenori Kimura

Kozo Yoshida

Nobuhisa Fukuda

Kiyoto Sawamura

Satoshi Suetsugu

Yoshio Nakai

Akira Fusano

The present invention relates to a medicament for treating neuropsychiatric diseases, comprising a compound of Formula (1): or a pharmaceutically acceptable salt thereof, as an active ingredient.

Substituted pyrazoles showing serotonin 5-HT receptor activity

Substituted lactams showing serotonin 5-HT receptor activity

Condensed lactam derivative

The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein Ris halogen, etc.; Ris H, etc.; Gis &#x2014;N(R)&#x2014;, etc.; Gis &#x2014;CO&#x2014;, etc.; Gis &#x2014;C(R)(R)&#x2014;, etc.; Gis oxygen, etc.; Ris optionally substituted Calkyl, etc.; Rand Rare independently the same or different, H, etc.; Ris H, optionally substituted Calkyl, etc.; R, R, Rc and Rare independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.]

Bicyclic heterocyclic derivative

Growing community of inventors

Kashihara, Japan

Junya Ikeda