Arizona State University

Leland Stanford Junior University

Mayo Foundation for Medical Education and Research

The United States Government As Represented by the Department of Veterans Affairs

Arizona Board of Regents, a Body Corporate

Junseok Chae

Michael N Kozicki

Shiyi Liu

Bruce E Rittmann

Alfredo Quinones-Hinojosa

Hyung-Sool Lee

Joseph Chihping Liao

Tito Vivas-Buitrago

Seokheun Choi

Jennie Appel

ElectroCorticoGraphy (ECoG) sensors and uses are disclosed. These ECoG arrays, systems, and processes may be operable or configured to: i) simultaneously record neural signals while providing stimulation on specific portions of the cortex using a user-guided stimulator; ii) acquire neural signals over a large cortex area; iii) provide individual or group stimulation while concurrently receiving neural feedback; and/or iv) acquire neural signals at a setting remote from the neural source using wireless or other communication techniques.

Contour electrocorticography (ECoG) array

A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.

Low-voltage microfluidic valve device and system for regulating the flow of fluid

Fully-passive sensor systems that receive an input electromagnetic signal and return an output electromagnetic signal are described. The sensor systems can be used to measure pressure in biological or non-biological systems.

Fully-passive pressure sensors and methods for their use

Systems, devices, and methods involving cardiac pace making are provided. Implantable wireless pace making systems, devices, and methods using electromagnetic waveforms to interact with subcutaneous implanted sensors or stimulators, or both, are described. Systems, devices, and methods can include wireless, miniaturized, battery-free, radiofrequency (RF) microwave activated, sensors or stimulators or integrated sensor/stimulators that are implanted in multiple thoracic cavity locations, and interact with a remote pace making control-module or multiple modules.

Wireless cardiac pace making

Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.

Method of screening cancer cells using wrinkle patterns on a thin membrane

A microbial fuel cell includes an anode portion having an anode and a cathode portion having a cathode. The anode is configured to support an electrically conductive biofilm matrix. A cation exchange membrane is positioned between the anode and the cathode. The anode portion and the cation exchange membrane define an anode chamber having a volume of between about 1 &#x3bc;L and about 100 &#x3bc;L and configured to receive an anolyte. The cathode portion and the cation exchange membrane define a cathode chamber having a volume of between about 1 &#x3bc;L and about 100 &#x3bc;L and configured to receive a catholyte. The microbial fuel cell is configured to achieve a Coulombic efficiency of at least 30% and/or a power density of at least of 4.7 &#x3bc;W/cm. The microbial fuel cell is a microelectromechanical system and can be fabricated in an automated production process.

Micro-sized microbial fuel cell

The present invention relates generally to microphone devices useful, for example, in hearing aid devices. The present invention relates more particularly to tunable microphone devices, and methods used to tune them. One aspect of the present invention is a microphone device that includes at least one microphone element. Each microphone element comprises a diaphragm suspended by a substrate; a solid electrolyte disposed on the diaphragm; an anode electrically coupled to the solid electrolyte; and a cathode electrically coupled to the solid electrolyte. The solid electrolyte is disposed between the anode and the cathode, such that ions flowing from the anode to the cathode travel through the solid electrolyte and electrons can flow in the opposite direction.

Growing community of inventors

Scottsdale, AZ, United States of America

Junseok Chae