National Institute of Advanced Industrial Science and Technology

Nissan Chemical Industries Limited

Nissan Chemical Corporation

Kyoto Institute of Technology

Junko Katayama

Taito Nishino

Yoshiomi Hiroi

Yoichi Kumada

Hiroaki Tateno

Ayako Aihara

Natsuki Abe

Kazutaka Matoba

Provided is a highly sensitive and less expensive lectin-immobilized base material (for example, a lectin plate), such as lectin-immobilized base material having stable qualities and being able to be sufficiently washed after a target sugar chain-containing antigen binds thereto. Further provided is a method for immobilizing lectin to a base material therefor. Particularly provided are: a method whereby a lectin-peptide fusion, in which a peptide capable of adsorbing to a base material surface such as a polystyrene (PS) tag is fused with the N-terminal side or C-terminal side of lectin capable of recognizing a target sugar chain, is immobilized on the peptide side to a base material; and a lectin-immobilized base material produced by this method. By using the lectin-immobilized base material, a target sugar chain-containing antigen can be highly sensitively and evenly measured and, moreover, target sugar chain-containing cells, etc. can be separated (concentrated and harvested).

Method for immobilizing lectin

The invention provides a coating agent for a flow passage which comprises a copolymer containing a recurring unit which contains an organic group of the formula (a) wherein Uand Uare defined herein, and a recurring unit which contains an organic group of the formula (b) wherein U, U, U, and Anare defined herein. The invention also provides a flow passage device having the coating agent for a flow passage on at least part of an inner surface of a flow passage, a platelet-producing flow passage device and a method for manufacturing the same.

Coating agent for flow passage

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Tokyo, Japan

Junko Katayama