Tokyo Gas Company Limited

Junko Hirayama

Kenji Maeda

Tadashi Kohno

Isaburo Hosoi

Asuka Ito

Kunihiko Shibata

Ito Asuka

A diagnostic agent for pancreatic exocrine function comprising a dipeptide represented by the following formula (I):X&#x2014;R&#x2014;Y&#x2003;&#x2003;(I)or a pharmaceutically acceptable salt thereof,

Diagnostic agents for pancreatic exocrine function

A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from the carrier when exposed to the action of a pancreatic exocrine function-related factor.

Preparation comprising albumin esterified with a labeled substance for diagnosis of pancreatic exocrine function

The present invention provides aC-labeled oligosaccharide or polysaccharide or a salt thereof excluding U&#x2014;C-maltose,C-starch, 1-C-maltotetraose and 1-C-amylose; a derivative of theC-labeled oligosaccharide or polysaccharide or salt thereof; aC-labeled inclusion complex or a salt thereof, which comprises a cyclodextrin or a modified derivative thereof as a host molecule; aC- orC-labeled fluorescein ester compound or a salt thereof; and a diagnostic agents for pancreatic exocrine function comprising these compoundsC- orC-labeled.

Method for diagnosis of pancreatic exocrine function

A diagnostic reagent for use in the evaluation of a pharmacological effect of a medicine containing a pharmaceutical agent including an enzyme, an enzyme inhibitor or a receptor ligand or a prodrug of the pharmaceutical agent is provided. Further, a method of screening pharmaceutical agents each comprising an enzyme, an enzyme inhibitor or a receptor ligand and/or prodrugs of the pharmaceutical agents is provided.

Method of evaluating pharmacological effects of medicine

Preparations for diagnosis extrapancreatic secretory function

The present invention relates to a diagnostic agent for diabetes, which comprises glucose labelled with C at a specific position, or pyruvic acid labelled with C at least one specific position. According to the present invention, there is provided a diagnostic agent for diabetes which can be used safely without side effects to give accurate results immediately with less physical pains on the subject. The present diagnostic agent for diabetes can distinguish between healthy persons and patients with diabetes even under the circumstances where the patients are easily missed, and further it can determine the type of diabetes (insulin-dependent type or insulin-independent type).

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Tokyo, Japan

Junko Hirayama