Powerex Corporation

Zensei Pharmacuetical Industries Co., Ltd.

Junji Yamazaki

Yoshio Nakano

Masaya Hizaki

Tomohiro Hayashida

Naotoshi Kinoshita

Provided are functional drug-containing particles which can be compressed into tablets and in particular, to orally disintegrating tablets by employing any of a dry molding method, a wet molding method, or a humidifying drying method. The functional drug-containing particles comprise substantially spherical drug-containing particles essentially including drug and a binder, the functional drug-containing particles including a functional polymer film selected from the group consisting of an enteric film, a release control film, and a bitter taste masking film, an average particle diameter of said functional drug-containing particles being 400 &#x3bc;m or less, a particle diameter ratio D/Dof the functional drug-containing particles with respect to particle size distribution calculated on a volumetric basis being 1.65 or more, or a coefficient of variation in particle diameters being 24% or more.

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Osaka, Japan

Junji Yamazaki