Fuji Photo Film Company, Limited

Jeol Ltd.

Kasei Optonix, Ltd.

Junji Miyahara

Hisatoyo Kato

Nobufumi Mori

Kenji Takahashi

Yuichi Hosoi

Takashi Nakamura

Seiji Matsumoto

Noboru Kotera

Satoshi Arakawa

Hisashi Shiraishi

Tetsuo Oikawa

Yoshiyasu Harada

Shusaku Eguchi

Syusaku Eguchi

Nobuyoshi Nakajima

Shigeru Saotome

Terumi Matsuda

Takayuki Katoh

Toshitaka Aagano

Katsuhiro Kohda

Keiichi Suzuki

Masayuki Shimizu

Masahiro Ohnishi

Norio Miura

Akira Kitada

Hirokazu Saito

Hisashi Yamazaki

Masanori Teraoka

Hiroyuki Toda

An autoradiographic gene-screening method employing a hybridization process, which comprises:

Autoradiographic gene-screening method

An autoradiographic process for obtaining information on one or two dimensional location of radioactively labeled substances contained in a sample selected from the group consisting of tissue of an organism and a medium containing tissue of an organism and/or substances such as DNA originating from an organism, which comprises: placing said sample and a stimulable phosphor sheet having a phosphor layer comprising a stimulable phosphor dispersed in a binder together in layers for a certain period to cause said phosphor sheet to absorb at least a portion of radiation energy emitted by the radioactively labeled substances in said sample; scanning said phosphor sheet with an electromagnetic wave to release at least a portion of radiation energy stored in said phosphor sheet as stimulated emission; and detecting the stimulated emission to obtain locational information on the radioactively labeled substances in the sample.

Autoradiographic process

A rare earth element activated complex halide phosphor and a radiation image storage panel having a fluorescent layer comprising the phosphor, which phosphor is represented by the formula:

Phosphor

Each of two-dimensional sensors is exposed to an electron beam, which has passed through a sample, in a vacuum in order to store the energy from the electron beam on the two-dimensional sensor, and is then exposed to light or heat in order to release the stored energy as emitted light. The emitted light is photoelectrically detected and an image signal is thereby obtained which represents an electron microscope image of the sample. Read-out conditions which are to be used when the emitted light is detected are determined from an electron beam exposure amount which was set when the energy from the electron beam was stored on each two-dimensional sensor. Signals representing the read-out conditions determined for the two-dimensional sensors are stored in a storage device so that it is clear which read-out conditions correspond to which two-dimensional sensor. When light emitted by a two-dimensional sensor is to be detected, a signal which represents the read-out conditions corresponding to the two-dimensional sensor is read from the storage device, and the read-out conditions are set.

Electron microscope image recording and read-out method

A radiographic intensifying screen comprising a support and a phosphor-containing resin layer provided thereon, in which the void ratio of said phosphor-containing resin layer is reduced in comparison with an ordinarily prepared phosphor-containing resin layer having the same binder-phosphor ratio and formed by a coating procedure conducted under an atmospheric pressure. The void ratio is not more than 85% of the void ratio of the ordinarily prepared phosphor-containing resin layer for a phosphor-containing resin layer which contains a resinous binder and a phosphor in a weight ratio of 1:1 to 1:25, the ratio of 1:25 being exclusive, and the void ratio is not more than 90% for a phosphor-containing resin layer which contains a resinuous binder and a phosphor in a weight ratio of 1:25 to 1:100.

Radiographic intensifying screen and process for the preparation of the

A radiation image storage panel comprising a support and a phosphor layer provided thereon which comprises a binder and a stimulable phosphor dispersed therein, characterized in that a light-reflecting layer containing a white pigment is provided between the support and the phosphor layer and that said light-reflecting layer is colored with a colorant capable of absorbing a portion of stimulating rays for the stimulable phosphor.

Radiation image storage panel

An electron microscope has a two-dimensional sensor located at the image-formation plane. The two-dimensional sensor stores electron beam energy and emits light upon exposure to light or heat. The filament is located at a position displaced from the principal optical axis of the electron beam so that the image of the filament may not be recorded on the two-dimensional sensor. The two-dimensional sensor is, for example, made of stimulable phosphor.

Electron microscope

A radiation image storage panel comprising a support and a stimulable phosphor-containing resin layer provided thereon, in which the void ratio of said stimulable phosphor-containing resin layer is reduced in comparison with an ordinarily prepared stimulable phosphor-containing resin layer having the same binder-phosphor ratio and formed by a coating procedure conducted under an atmospheric pressure. The void ratio is not more than 85% of the void ratio of the ordinarily prepared stimulable phosphor-containing resin layer in which a resinous binder and a stimulable phosphor are contained in a weight ratio of 1:1 to 1:25, the ratio of 1:25 being exclusive, and the void ratio is not more than 90% for a stimulable phosphor-containing resin layer in which a resinous binder and a stimulable phosphor are contained in a weight ratio of 1:25 to 1:100.

In a system for recording and reproducing an electron microscope image, a two-dimensional sensor for storing electron beam energy is exposed to an electron beam passing through a sample in a vacuum to have the electron beam energy stored in the two-dimensional sensor. The two-dimensional sensor is then exposed to light or heated while the vacuum is maintained to release the stored energy as light emission. The light emitted by the two-dimensional sensor is photoelectrically detected to obtain an electric signal for reproducing a visible image.

Method and apparatus for recording and reproducing electron microscope

In a system for outputting an electron microscope image, a two-dimensional sensor for storing electron beam energy thereon is exposed to an electron beam passing through a specimen in a vacuum to have the electron beam energy stored on the two-dimensional sensor, and is then exposed to light or heat to release the stored energy as light emission. The emitted light is photoelectrically detected to obtain image signals, and an electron beam image of the specimen is output on the basis of the image signals. The specimen is divided into a plurality of divisions, and the storage of the electron beam energy is carried out for each of the divisions. The image signals obtained at the divisions are combined to form composite image signals that represent an overall specimen image formed by a group of the divisions, and the image signals at the divisions are corrected so that signal values of the boundary areas of adjacent divisions become approximately equal to each other.

Electron microscope image output method and apparatus

A radiation image read-out apparatus comprises an optical system for scanning a stimulable phosphor sheet carrying a radiation image stored therein by stimulating rays, a light guide member for guiding light emitted by the stimulable phosphor sheet upon exposure to stimulating rays, and a photoelectric converter for detecting the guided light. A film for preventing reflection of stimulating rays is closely contacted with a light input face of the light guide member. Or, a filter for absorbing the stimulating rays reflected by the stimulable phosphor sheet and transmitting the light emitted by the stimulable phosphor sheet is positioned between the stimulating ray incidence point on the stimulable phosphor sheet and the light input face of the light guide member.

Radiation image read-out apparatus

A transmission-type electron microscope using a sensitive two-dimensional sensor in its micrograph-taking section acts as a recording medium for an electron beam. When the sensor is illuminated with an electron beam, it stores the energy of the beam. When the sensor is subsequently illuminated with light, it releases the stored energy as light. In accordance with the invention, at least a portion of the micrograph-taking section includes a member for reducing the amount of x-rays produced or a member for absorbing x-rays to shield the sensor from x-rays.

A method for detecting radiation image which comprises steps of: causing a radiation image storage panel which comprises a phosphor layer containing a stimulable phosphor to absorb a radiation having passed through an object or radiated from an object; placing said radiation image storage panel and a photosensor composed of numerous photosensitive elements in regular and two-dimensional arrangement together in layers, and irradiating the panel with an electromagnetic wave to release the radiation energy stored in the panel as stimulated emission; and photoelectrically detecting the stimulated emission with said photosensor. A method for detecting radiation image using a radiation image detector which comprises a photosensitive member composed of numerous photosensitive elements and a phosphor layer containing a stimulable phosphor provided thereon is also disclosed.

Method for detecting radiation image

A transmission-type electron microscope comprises a lens system including an electron gun for producing an electron beam that is focused and directed to a specimen. The lens system forms a magnified electron optical image of the specimen from the electron beam transmitted through the specimen. A two-dimensional sensor is mounted in the plane in which the magnified image is formed, the sensor acting to store the energy of the electron beam impinging on it and to release the stored energy as light when illuminated with light or heated. An electron beam-deflecting means is mounted in the lens system and acting to tilt the focal plane in which the magnified lens image is formed, in such a way that a straight line extending from the main optical axis of the electron beam between the electron gun and the specimen does not interset the two-dimensional sensor.

Growing community of inventors

Kaisei, Japan

Junji Miyahara