Japan Science and Technology Agency

Junji Hirota

Katsuhiko Mikoshiba

Hideaki Ando

Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP) receptor (IPR), preferably with a regulation domain of IPR; analysis of the function of IPR; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IPR. In particular, control of the activity of intracellular Carelease. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP) receptor (IPR), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calcium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Control of function of intracellular Ca ion

Analysis of substance capable of binding with inositol-1, 4,5-triphosphate (IP) receptor (IPR), preferably with a regulation domain of IPR; analysis of the function of IPR; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IPR. In particular, control of the activity of intracellular Carelease. More specifically, a regulator for the activity of inositol-1,4, 5-triphosphate (IP) receptor (IPR), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calsium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

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Osaka, Japan

Junji Hirota