Nitto-denko Corporation

Sasaki Chemical Co., Ltd.

Eisai R&d Management Co., Ltd.

Fujimoto Co., Ltd.

Junichi Sekiya

Hitoshi Akemi

Yoshihiro Iwao

Keigo Inosaka

Akinori Hanatani

Makoto Kai

Katsuya Kume

Junichi Saito

Mitsuhiro Kanada

Tomohide Banba

Natsuki Kobayashi

Yoshifumi Hosaka

Hidetoshi Kuroda

Mami Ikeya

Tsuyoshi Kasahara

Ryo Hashino

Jun Ishikura

Sachiko Sakamoto

Yu Tachikawa

Satoshi Ameyama

Toshinobu Tsuda

Raito Funayama

Akio Takada

Yasushi Buzoujima

Koji Nakamura

Sumiyo Maruyama

Satoko Washiro

Sumiyo Nishi

A stable percutaneous absorption-type pharmaceutical preparation for percutaneous administration of drugs except for selegiline and selegiline hydrochloride, which does not suffer a decrease in the cohesive force of the adhesive layer therein even in the presence of sweat components due to perspiration during wear and which is free from cohesive failure and resultant adhesive remaining when stripped off. A percutaneous absorption-type pharmaceutical preparation which comprises: a support; and an adhesive layer containing an adhesive, a metal chloride and a percutaneously-absorptive drug except for selegiline and selegiline hydrochloride, wherein the adhesive layer is subjected to a crosslinking treatment.

Percutaneous absorption-type pharmaceutical preparation

The patch according to an embodiment of the present invention includes: a support; and a pressure-sensitive adhesive layer on at least one surface of the support, wherein: the pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N-hydroxyalkyl(meth)acrylamide; a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 wt % to 90 wt % and a content of the N-hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 1 wt % to 20 wt %; and the monomer components are substantially free of a monomer having a carboxyl group.

Transdermal patch having a pressure-sensitive adhesive comprising (meth)acrylic acid alkyl ester, N-hydroxyalkyl(meth)acrylamide, and vinyl monomers

The main object of the present invention is to provide a patch package structure capable of stably retaining the physiologically active ingredient in a patch during preservation of the patch. This object can be achieved by employing the following constitution. To be specific, the present invention is a patch package structure including a patchand a packaging memberholding the patch, wherein the patchincludes a supportand an adhesive layerformed on at least one surface of the support, the packaging memberincludes a first package, the first packageincluding an acrylonitrile resin layer, a moisture-absorbing layerformed on the acrylonitrile resin layer, and a moisture impermeable layerformed on the moisture-absorbing layer, and the acrylonitrile resin layeris provided on the proximal side of the patch

Patch package structure

The main object of the present invention is to provide a patch package structure including a patch containing a physiologically active ingredient and a package housing the patch, which is capable of stably retaining the physiologically active ingredient in the patch during preservation. This object can be achieved by employing the following constitution. To be specific, the present invention is a patch package structure including a patchhaving an adhesive layer containing an organic liquid component, and a packaging memberhousing the patch, wherein the packaging memberincludes a first package, the first packageincluding an acrylonitrile resin layer, a moisture-absorbing layerformed on the acrylonitrile resin layer, and a moisture impermeable layerformed on the moisture-absorbing layer, and the acrylonitrile resin layeris provided on the proximal side of the patch

The present invention provides an adhesive capable of affording an adhesive layer showing reduced stickiness, reduced cohesive failure and the like. An adhesive containing a copolymer obtained by copolymerizing monomers containing a (meth)acrylic acid alkyl ester as a main component, and a vinyl monomer having a hydroxyl group and/or a carboxyl group and which has an average molecular radius of not less than 70 nm as measured by a multi angle laser light scattering method.

Adhesive and laminate

The invention provides an inorganic powder-containing resin composition capable of forming a dielectric layer having high light transmittance and excellent in surface smoothness. The invention also provides a film-forming material layer, a transfer sheet and a dielectric layer, which comprise the composition, a method of producing a substrate having a dielectric layer formed thereon, and a substrate having a dielectric layer formed thereon. The inorganic powder-containing resin composition comprises inorganic powder, a binder resin, and a phosphorus compound represented by formula (1): wherein R, Rand Rindependently represent H, an alkyl group, an alkylaryl group, NH(ammonium) or &#x2014;(CHCHO)&#x2014;R, wherein n is 1 to 15, and Rrepresents H, an alkyl group, an alkylaryl group or a (meth)acryloyl group.

Inorganic powder-containing resin composition, a film-forming material layer, a transfer sheet, method of producing a substrate having a dielectric layer formed thereon, and a substrate having a dielectric layer formed thereon

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Ibaraki, Japan

Junichi Sekiya