Akita University

Olympus Corporation

Arkay, Inc.

Junichi Ogawa

Satoru Motoyama

Masatomo Miura

Tomoaki Ueda

Yoshihiro Minamiya

Yoshihisa Katayose

Reijiro Saito

Shuichi Kamada

The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.

Method for determining lymph node metastasis in cancer or risk thereof and rapid determination kit for the same

The apparatus of the present invention comprises: an excitation device which excites the measurement site with a local direct-current or alternating-current magnetic field, and a plurality of magnetic field detection devices which are disposed in proximity to each other to measure the magnetic field component that is perpendicular to the exciting magnetic field. A magnetic fluid that possesses paramagnetism is injected from the outside into a substance in which a fluid can flow, and the local magnetic field gradient is then measured while the injected magnetic fluid is excited by the application of a direct-current or alternating-current magnetic field from the outside, thus measuring the presence or absence of distortion of the local magnetic field distribution arising from the fact that the specific magnetic permeability of the magnetic fluid injected into the substance is higher than that of the surrounding substance, so that sites where large amount of the magnetic fluid has accumulated are identified in a non-invasive manner without being affected by external magnetic noise.

Magnetic fluid detection method and magnetic fluid detection apparatus

Growing community of inventors

Akita, Japan

Junichi Ogawa