University System of Maryland

Jung Yeon Han

Donald Lad DeVoe

In an embodiment, a microfluidic chip includes a capillary is disposed between upper and lower substrates, where the capillary includes a porous monolithic structure disposed within the capillary, and a clamp structure is defined within the channel and engages with the capillary. The clamp structure comprises a thermoplastic material that, when heated to a selected temperature, deforms around the capillary to secure the capillary in alignment with the channel. In another embodiment, a microfluidic chip includes a porous monolithic brick disposed between first and second substrates, where each of the first and second substrates includes a channel extending through the substrate to the brick structure to provide a fluid flow path through the each of the first substrate, the second substrate and the brick structure.

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College Park, MD, United States of America

Jung Yeon Han