Oscotec Inc.

Korea Research Institute of Chemical Technology

Jung-Keun Kim

Se-Won Kim

Seon-Yle Ko

Hyung-Gun Kim

Dong-Heon Baek

Hyuk Jae Lee

Jung Nyoung Heo

Bum Tae Kim

Yeon Soo Lee

Yong Ki Min

Sunhwa Chang

No Kyun Park

Dong Sik Jung

Jong-Yeo Kim

Byung-Eui Lee

Seong-Hee Ko

Youngnim Choi

Heejong Woo

The present invention relates to a herbal mixture extract of Rehmanniae Radix Preparata and Acanthopanacis Cortex and a composition comprising the same for the prevention and treatment of osteoporosis. The herbal mixture extract of the present invention enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts, so that it can be effectively used for the prevention and treatment of osteoporosis.

Herbal mixture extract of rehmanniae radix preparata and acanthopanacis cortex and a composition comprising the same for prevention and treatment of osteoporosis

The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases.

Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyacrylate derivatives

The present invention relates to a herbal mixture extract ofPreparata andand a composition comprising the same for the prevention and treatment of osteoporosis. The herbal mixture extract of the present invention enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts, so that it can be effectively used for the prevention and treatment of osteoporosis.

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Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyactylate derivatives

The present invention relates to an extract of an herbal mixture ofand, and a method for treating arthritis using the extract as an effective ingredient. The extract of the herbal mixture of the present invention can effectively inhibits the release of inflammatory substances and the synthesis of cartilage destroying substance as well as the progress of arthritis.

Herbal mixture extract of notoginseng radix, rehmanniae radix preparata and acanthopanacis cortex and composition comprising the same for prevention and treatment of arthritis

The present invention relates to a herbal mixture extract ofandand a composition for prevention and treatment of periodontal disease containing the herbal mixture extract as an active ingredient, more precisely, a herbal mixture extract having activities of inhibiting the generation and activation of osteoclasts by enhancing the expression of osteoprotegerin (OPG) in osteoblasts, preventing alveolar bone from destruction by inhibiting the proliferation of osteoclasts and maintaining the growth of periodontal ligament cells and gingival fibroblasts, and a composition for prevention and treatment of periodontal disease containing the above mixture as an active ingredient.

The present invention relates to a composition comprising Notoginseng radix extract for preventing and treating arthritis as an effective ingredient. Notoginseng radix extract of the present invention inhibits release of tumor necrosis factor-alpha (TNF-&#x3b1;) and is the death of activated T-cells only, so that it can be effectively used for the production of a medicine for preventing and treating arthritis and health food as well.

Composition comprising Notoginseng radix extract for preventing and treating of arthritis as an effective ingredient

Growing community of inventors

Seongnam-si, South Korea

Jung-Keun Kim