Dongwha Pharm. Ind. Co., Ltd.

Jung A Lee

Hyun S Hwang

Sung June Yoon

Dong Rack Choi

Yong Ho Chung

Dug Keun Lee

Hae Ran Yun

Hee Soon Lee

Sang Hun Jung

Moon Sun Lee

Chung Ha Choi

Eun Yi Moon

The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which - -, R.sub.1, and R.sub.2 are as defined in the specification.

Arylsulfonylimidazolone derivatives as an antitumor agent

The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which ----, R.sub.1, and R.sub.2 are as defined in the specification.

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Seoul, South Korea

Jung A Lee