Vmware, Inc.

The Florida State University Research Foundation, Inc

Junfeng Wang

Yu Wang

Qi Liu

Li He

Binghe Wang

Jin He

Shilong Zheng

Xiangjun Song

Xiangdong Che

Nanting Ni

Hanjing Peng

Minyong Li

Chung-Dar Lu

Han-Ting Chou

Yunfeng Cheng

System and methods for replicating and enforcing license information in a computer cluster are described. The method may include: receiving, by a core-node in the computer cluster, a plurality of peer-license-info from a plurality of peer-nodes selected from a plurality of cluster nodes. Each of the plurality of peer-license-info may include license-info collected by and associated with a corresponding one of the plurality of peer-nodes. The method may include generating, by the core-node, a first cluster-license-info based on the plurality of peer-license-info. The method may further include propagating, by the core-node, the first cluster-license-info to each of the plurality of peer-nodes. The first cluster-license-info is configured for detecting license violations among the plurality of cluster nodes.

Cluster-wise license information replication

The present disclosure encompasses compounds and compositions that are useful as specific AI-2 antagonists for the control of bacterial quorum sensing. Although the AI-2 antagonists according to the present disclosure may not have bactericidal effect, their ability to attenuate virulence, drug resistance, and/or biofilm formation have therapeutic benefits. In addition, the AI-2 antagonists of the present disclosure can also be used as tools to probe bacterial AI-2 functions. The present disclosure also encompasses methods for inhibiting or attenuating microbial virulence, biofilm formation, and drug resistance. The methods are suitable for preventing bacteria from accruing and forming extensive biofilms that may be a health or hygiene hazard or a physical issue, such as in the blockage of water or fuel lines.

Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria

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Beijing, China

Junfeng Wang