Cygnus, Inc.

Cygnus Terapeutic Systems

Jun Xia

Chia-Ming Chiang

Gary W Cleary

Janan Jona

Ooi Wong

Kathleen C Farinas

A combination permeation enhancer for increasing the permeability of skin to sex steroids such as estrogens and progestogens comprising a polyhydric thioalcohol of 2 to 6 carbon atoms having at least one mercapto group and at least one hydroxy group and an aliphatic carboxylic acid of 8 to 24 carbon atoms or an ester thereof.

Skin permeation enhancer composition for use with sex steroids

A skin or buccal patch for providing nicotine replacement therapy which comprises a matrix type laminated composite in which the matrix is composed of a mixture of nicotine in a polymer wherein the amount of nicotine in the matrix, diffusion coefficient of nicotine in the matrix and the thickness of matrix are such that the release of nicotine is: (1) controlled by the patch; (2) rapid and at a relatively high flux over the prescribed wearing time of patch; and (3) such that a substantial proportion of the nicotine initially in the patch has been released at the end of the prescribed wearing time.

Method and device for providing nicotine replacement therapy

Growing community of inventors

Edison, NJ, United States of America

Jun Xia