Fina Technology, Inc.

University of California

Jun Wang

Kevin Patrick Kelly

Kenneth Paul Blackmon

Sivadinarayana Chinta

Fenyong Liu

Xavier Roumeau

Ryan Jones

Fabrice Déhais

Hong Jiang

A method for determining a TAN-IR for naphthenic acids in crude oil or crude oil fraction may include determining an IR spectrum of a sample of the crude oil or crude oil fraction. The method may include determining an IR spectrum of a neutralized sample of the crude oil or crude oil fraction. The method may include utilizing the IR spectra of the sample and the neutralized sample to determine a modified TAN-IR.

Determining modified TAN-IR in crude oil

A process is disclosed that includes reacting a C1 source with n-butene to form a C-5 diolefin.

Method of forming C5 di-olefins

Infectious human cytomegalovirus (HCMV) were isolated in vitro from a pool of randomized sequences after sixteen or 21 cycles of selection and amplification. The ligands characterized exhibited high HCMV-binding affinity in vitro and effectively inhibited viral infection in tissue culture. Several ligands blocked viral entry. Their antiviral activity was also specific as the ligands only reacted with strains of HCMV, but not with the related herpes simplex virus 1 and human cells. Moreover, the ligands recognize several different epitopes. Thus, RNA ligands can function to bind to a human virus and block viral infection. The screening method may utilize the novel features of binding to intact infectious virus, partitioning the bound polynucleotides from unbound by passing through a porous filter, and enhancing the release of bound polynucleotides by treatment with protease.

Polynucleotide ligands as anti-viral agents

Growing community of inventors

Houston, TX, United States of America

Jun Wang