Postech Academy-industry Foundation

Shin Poong Pharmaceutical Co., Ltd.

Jun Seok Yeom

Sei Kwang Hahn

Young Soo Park

Jung Ho Je

Il Hwan Cho

Byung Su Kim

Eun Ju Oh

Byung Mook Weon

Eui Jin Hwang

Jung Kyu Park

Moo Seok Seo

So Eun Chang

Jang Sik Shin

The present invention relates to a filler composition for tissue reinforcement, including hyaluronic acid and alkylene diamine crosslinked hydrogel. The filler composition exhibits the positive physical properties required for tissue reinforcement, such as biocompatibility and swelling ability, as well as useful effects in that the same can remain in vivo for a long time.

Filler composition for tissue reinforcement

Disclosed is a method for ablating hyaluronan-based hydrogels with X-rays, the method comprising the steps of: (a) preparing hyaluronan-based hydrogels; and (b) performing X-ray irradiation to the hyaluronan-based hydrogels to induce a degradation of the hyaluronan-based hydrogels by a gel-to-sol transition during the X-ray irradiation. Disclosed is also a method for fabricating three-dimensional microchannels of hyaluronan hydrogels with a finely tunable X-ray ablation technique.

X-ray ablation of hyaluronan hydrogels

Growing community of inventors

Jinju-si, South Korea

Jun Seok Yeom