Beijing Unidiag Technology Inc

International Business Machines Corporation

Baylor College of Medicine

Institute of Radiation Medicine, China Academy of Military Medical Sciences

Jun Qin

Chen Hui Xu

Lei Song

Yu Fen Yuan

Chen Ding

Shuan Shuan Chen

Li Hong Qi

Qiongming Liu

Mingwei Liu

Wanlin Liu

A computer implemented method for creating a prioritized global conversation thread in a data processing system comprising a processing device and a memory comprising instructions which are executed by the processing device, the method can comprise receiving a plurality of messages from a plurality of message channels; combining a plurality of subsets of the plurality of messages to form a plurality of conversation threads, wherein each subset of the plurality of messages forms one of a plurality of the plurality of conversation threads; extracting a plurality of important messages from the plurality of conversation threads, wherein at least one important message of the plurality of important messages is extracted from each of the plurality of conversation threads; storing the plurality of important messages; determining, for each of the plurality of important messages, a message priority; and displaying, to a user, the plurality of important messages based on the message priority.

Systems and methods for intelligent message interaction

An electrochemiluminescence immunoassay system and a flow-through cell unit () thereof. The flow-through cell unit () comprises a working electrode (), a counter electrode () and a reference electrode (), wherein the working electrode () and the counter electrode () are vertically provided, and there is a liquid flow path between the two electrodes. When an electrochemical reaction occurs, and when reactants are evenly distributed on the working electrode () for a test. After the flow-through cell is cleaned, the liquid flow path is unblocked, so that the cleaning effect is better. A porous structure is provided on a connection surface where the reference electrode () is in communication with the liquid flow path, and the porous structure makes the reference electrode () have a good electrical conductivity, and prevents the reference electrode () from early ageing, and improves the durability of the flow-through cell unit ().

Electrochemiluminescence immunoassay system and flow-through cell component thereof

An electrochemiluminescence immunoassay method is disclosed and uses a full reaction of a Ru(bpy) marked protein-primary antibody, a biotinylated protein-secondary antibody to be tested, and a sample to be tested; addition of a Streptavidin-coated magnetic particle to form a complex comprising an antigen, an antibody, and a magnetic particle; adsorption to an electrode surface by the magnetic particle; addition of a dibutyl ethanolamine solution; and testing by an electrochemical method. Also disclosed is a corresponding electrochemiluminescence immunoassay detection kit.

Electrochemiluminescence immunoassay method

The present invention provides a method for enrichment and isolation of endogenous transcription factors and their complexes. Also, this invention provides corresponding tandem arrays of concatenated transcription factor response elements (catTFRE). The method employs the property of transcription factors binding to sequence-specific DNA elements during regulation of gene expression. The catTFREs are designed and synthesized as concatenate dual copies of DNA response elements for various transcription factors. The DNA sequence of synthesized catTFRE is cloned to a target vector. Biotinylated catTFRE with 200 bp arms is prepared by PCR strategy. For enrichment and isolation of endogenous transcription factors and their complexes, the biotinylated catTFRE is immobilized to streptavidin-coated magnetic beads and then incubated with nuclear extract. Thereby endogenous transcription factors and their complexes are isolated from nuclear extract. Identification by mass spectrometry or other functional characterization can be further performed according to the application purposes.

Method for enrichment and isolation of endogenous transcription factor and complexes thereof and corresponding tandem arrays of concatenated transcription factor response elements

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Beijing, China

Jun Qin