Toyama Chemical Co., Ltd.

Jun Nitta

Isamu Saikawa

Chosaku Yoshida

Takako Hori

Hisatsugu Tsuda

Shohachi Murakami

Joji Nakano

Ryuko Takeno

Yasuo Kiba

Sumiko Kishimoto

Hirokazu Narita

Yasuo Watanabe

Yozo Todo

Yoshinori Konishi

Shinzaburo Minami

Isao Kitayama

Mikako Miyajima

Hideyoshi Nagaki

Yoshikazu Fukuoka

Hiroyasu Takagi

Shunjiro Misumi

Nobuyuki Matsubara

Yoriko Nagai

Fumihiko Iino

This invention relates to a novel pyridone carboxylic acid derivative having a substituted or unsubstituted cyclopropyl group at the 10-position of pyridobenzoxazine, pyridobenzothiazine or pyridoquinoxaline and a salt thereof, a process for the production thereof and an antibacterial agent comprising the same.

Pyridone carboxylic acid derivatives and salts thereof, process for

This invention relates to a novel 4-oxo-1,4-dihydronicotinic acid derivative ##STR1## or a salt thereof, wherein R.sup.1 is hydrogen or carboxyl-protecting group;

4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and

A 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative represented by the formula: ##STR1## and an acid addition salt thereof have excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.

1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives, acid addition salts

Novel 1-(4-piperidiniobenzyl)-2,3-dioxopiperazine derivatives or acid

A 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative represented by the formula: ##STR1## and a salt thereof have excellent carcinostatic activity but a low toxicity. Therefore, said compounds are useful as medicines and also as intermediates.

1-(4-Aminobenzyl)-2,3-dioxopiperazine derivatives and salts thereof

4-[4-(Thiazolyl-amino)benzyl]-2,3-dioxopiperazine derivatives, acid

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Namekawa, Japan

Jun Nitta