Chinese Academy of Sciences

Hangzhou Hikvision Digital Technology Co., Ltd.

Tyk Medicines Inc.

Zhejiang University

Hefei Cas Ion Medical and Technical Devices Co., Ltd

Heye Health Technology Co., Ltd.

Guangdong Keprime Enerstore Ltd

Ningbo Meihe Information Technology Co., Ltd.

Tyk Medicines (zhengzhou), Inc.

Yuyao Yunjin Electric Co., Ltd.

Airdeer (hangzhou) Technology Co., Ltd.

Jun Li

Deyu Wang

Yuanhao Tang

Yuntao Song

Peng Chen

Lei Li

Feng Zhang

Xu Wang

Bin Wang

Yonghua Chen

Xin Chen

Kaizhong Ding

Jiang Li

Jian Zhou

Chengshan Niu

Lanjuan Li

Apeng Liang

Yusheng Wu

Rui Hu

Shuangsong Du

Yanfang Bi

Zhiqiang Jiang

Chunlong Zou

Chenyun Wang

Zhixiao Li

Zhixin Zhang

Zhongwei Guo

Shaopeng Zhou

Zhicheng Bi

Haitao Zhao

Chonghua Wang

Li Wan

Huahui Zhang

Xuedong Wu

Zongbao Wang

Wentao Shi

Qun Gu

Xianhui Zhang

Zhenlian Chen

Jinhua He

Lijiang Hu

Zhicai Fang

Maolin Zheng

A kinase inhibitor compound of formula I or a pharmaceutically acceptable salt, solvate, or prodrug thereof. The compound has good inhibitory activity on EGFR and Her2 exon 20 insertion mutation, EGFR exon 19 deletion and L858R point mutation of exon 21.

Compounds used as kinase inhibitors and application thereof

Plug socket

Provided is the compound represented by formula I, or tautomer thereof, or meso thereof, racemate thereof, and mixture of meso and racemate thereof, or enantiomer thereof, diastereomer, and mixture of enantiomer and diastereomer, or pharmaceutically acceptable salt thereof, or deuterate thereof. The compound of formula I can be used as a kinase inhibitor, as a drug for the treatment of ROS1, NTRK, ALK, and other kinase-mediated diseases.

3-oxadiazolyl substituted pyrazolo[1,5,a]pyrimidines for ROS1, NTRK, and ALK mediated diseases

Case for control device

Traffic proxy-based Internet of Things terminal key information leakage monitoring methods and systems, electronic devices, storage media, and computer programs. An example method includes: receiving a proxy request sent by an Internet of Things terminal, the proxy request including protocol related information of the Internet of Things terminal, and the protocol related information including part or all of device model information, service type information, and data packet information; according to the protocol related information of the Internet of Things terminal, determining a target protocol corresponding to the Internet of Things terminal; and allocating a target proxy service to the Internet of Things terminal according to the target protocol, and a usage state and an online state of each proxy service in a full traffic proxy pool, and performing key information monitoring on the traffic of the Internet of Things terminal by the target proxy service.

Information leakage monitoring method and system, and electronic device

A long tube plastic film bag for garbage cans and a packaging method thereof, and a packaging mold are provided. The long tube plastic film bag includes a long tube plastic film bag body and an outer packaging. The outer packaging is a film tube material. The film tube material includes a first opening and a second opening. One annular first groove is formed between the first opening and the second opening. An end of the long tube plastic film bag body is an open end, and another end is a sealed end. The long tube plastic film bag body is gathered toward the open end and stored in the first groove. The sealed end of the long tube plastic film bag body is extended out of the first groove of the film tube material.

Long tube plastic film bag for garbage can and packaging method thereof and packaging mold

Lamp

The present disclosure provides a state management method, a method for switching between a master application server and a backup application server, and an electronic device. In present disclosure, the management server updates the recorded backup application server state in time by querying for the connection state of the hot-backup connection between the master application server and the backup application server, and when the master application server is in failure, instead of immediately controlling the master application server and the backup application server to perform switching between the master and backup application servers, the management server controls the master application server and the backup application server to perform master-backup switching between the application servers according to the recorded backup application server state.

State management methods, methods for switching between master application server and backup application server, and electronic devices

Light bulb

The invention discloses a portable mobile decorative cylinder LED lamp, comprising a bottom base cover, a first upper base cover, a second upper base cover, a first base connector, a second base connector, a circular aluminum sleeve, a switch button, a driver board, an aluminum tripod base, light strips, an inner pipe, an outer pipe and a top cover. The upper end of the bottom base cover is mounted with the first upper base cover and the second upper base cover through screws, the first upper base cover and the second upper base cover are clamped, the first upper base cover and the second upper base cover are jointly mounted with the first base connector through screws, and the upper end of the first base connector is in contact with the second base connector.

Portable mobile decorative cylinder LED lamp

High voltage controller

A superconducting magnet system and a cyclotron using the same. The superconducting magnet system includes a cryogenic device, a superconducting device and a protecting module. The cryogenic device includes a refrigerating machine and a cryogenic container assembly. The cryogenic container assembly includes a first container end, a connecting tube and a second container end. The first container end is communicated with the second container end through the connecting tube. The superconducting device includes a superconducting coil arranged in the first container end and immersed in a liquid or gaseous cooling medium. The protecting module is connected to the superconducting coil and is configured to protect the superconducting coil if the superconducting coil suffers a quench.

Superconducting magnet system for cyclotron and cyclotron comprising ihe same

Portable soccer goal

The present disclosure relates to the technical field of equipment with a rotating magnetic field. Disclosed are a device with a high energy rotating magnet and a massage chair structure with a rotating magnet. The present disclosure includes a vertically driven revolving axle connected to a motor. A top end of the vertically driven revolving axle is connected to a gear set. The gear set meshes with a driving gear. A base revolving plate is fixed on an upper portion of the driving gear. A magnetic assembly is installed on the base revolving plate. The present disclosure offers improved physical performance, low cost, and an enhanced effect of magnetic therapy.

Device with high energy rotating magnet and massage chair structure with rotating magnet

A method of treating fulminant hepatic failure in a subject, includes administering a therapeutically effective amount of a pharmaceutical composition to the subject, wherein the pharmaceutical composition comprises a DLL4 cytokine. A method of treating liver failure, sub-acute liver failure, chronic liver failure or acute-on-chronic liver failure in a subject, includes administering an therapeutically effective amount of a DLL4 cytokine to the subject.

Method of treating fulminant hepatic failure using DLL4 cytokine

Growing community of inventors

Zhejiang, China

Jun Li