Small Machines

Seoul National University

Yonsei University

Small Machines Co., Ltd.

Jun Kyu Choi

Yong Kim

Chul Min Joo

Gyeong Woo Kang

Seung Ri Song

Su Jin Lee

Seung Soo Han

Kyung Hun Lee

Sun Woong Hur

Na Hyun Song

Sung Jun Lee

Choo Yeon Kim

Chang Hyuk Yoo

Jae Ha Shin

Hyung Jin Oh

Sunwoong Hur

Jin Kyu Seo

Oh Jun Gwon

The present invention provides a method of quantitatively analyzing an antigen, the method comprising: a step of mixing an assay sample comprising a target antigen, magnetic particles on which a first antibody subjected to an antigen-antibody reaction with the target antigen is immobilized, and beads on which a second antibody different from the first antibody is immobilized; a step of adding dropwise the mixed assay sample to a microchip for quantitatively analyzing an antigen; a step of introducing the microchip into a digital inline microscope-based detector comprising a magnetic force applicator and applying magnetism to the magnetic force applicator; and a step of detecting the beads using images acquired in the detector to count the number of the target antigens.

Microchip and device for quantitative analysis of antigen, and method for quantitative analysis of antigen using same

A microchip includes a body having an upper surface and a lower surface and a plurality of inner channels formed between the upper surface and the lower surface in which the plurality of inner channels include an input channel configured to receive an assay sample including target antigens and injected through a though hole, a reaction channel configured to be in fluid communication with the input channel and including magnetic particle-first antibody complexes to be subjected to a first antigen-antibody reaction with the target antigens, the magnetic particle-first antibody complexes including magnetic particles and first antibodies, and a detection channel configured to be in fluid communication with the reaction channel and including second antibodies to be subjected to a second antigen-antibody reaction with the immune complexes flowed from the reaction channel.

Microchip for analyzing fluids

Disclosed are a method of acquiring an image using a light-emitting element array and an apparatus therefor. The method of acquiring an image using a light-emitting element array includes reconstructing a first image from some images among source images, detecting a partial region containing a detection target object from the first image, acquiring partial-region images corresponding to the partial region from each of the source images, and reconstructing a second image from the partial-region images using the FPMP.

Method and device for acquiring image by using light-emitting element array

The present invention provides a method of quantitatively analyzing a target substance, the method including a step of irradiating a biochip, which includes a plurality of target substances excluding a fluorescence-labeled material, with light; a step of acquiring a plurality of low-resolution images for a region including the plurality of target substances using an image sensor; a step of acquiring a high-resolution image based on the plurality of low-resolution images; and a step of counting the plurality of target substances in the high-resolution image; and a device for quantitatively analyzing a target substance using the method.

Method for quantitatively analyzing target material and device for quantitatively analyzing target material by using same

Provided are a microscope apparatus and a method for correcting a position of a light source according to an exemplary embodiment of the present disclosure. The microscope apparatus for correcting the position of the light source according to the exemplary embodiment of the present disclosure includes: a light source unit which includes a light emitting element array including multiple light emitting elements and is configured to emit light to a subject; an optical unit which is disposed in parallel with the subject and configured to form an enlarged image of the subject to which the light is emitted; an image sensor which is configured to acquire the enlarged image of the subject by capturing the enlarged image formed by the optical unit; and a processor which is operably connected to the light source unit, the optical unit, and the image sensor and corrects a position of the light source unit based on the image acquired by the image sensor.

Microscope apparatus and method for correcting position of light source

There is provided a microscope apparatus and method for calibrating the position of a light source according to an embodiment of the present disclosure. A microscope apparatus according to an embodiment of the present disclosure includes: a light source unit configured to radiate light onto an subject and including a light emitting element array having a plurality of light emitting elements; an optical unit disposed in parallel with the subject and configured to form enlarged images of the subject receiving the radiated light; an image sensor configured to generate enlarged pictures of the subject based on the enlarged images formed through the optical unit; and a processor operably connected with the light source unit, the optical unit, and the image sensor, and calibrating a position of the light source unit based on a plurality of images generated by the image sensor.

Microscope apparatus and method for calibrating position of light source

Provided are molecule immobilization patterns and a method for forming the same, thereby reducing noise that may occur while analyzing a signal, being stable even at room temperature, and improving orientation of immobilized materials.

Molecule immobilization patterns and method for forming the same

The present disclosure relates to a capacitive element sensor and to a method for manufacturing same. More particularly, the present disclosure relates to a change in total capacitance brought about by the electrical charge of biomolecules attached to an electrode and to a sensor for measuring the change.

Capacitive element sensor and method for manufacturing same

The present invention relates to a transducer and a method for manufacturing same, and more particularly, to a transducer and to a method for manufacturing same, in which a first liquid and a second liquid are supplied such that, at the boundary therebetween, a deformation-generating part, including a perforated structure having one or more holes therein, is formed, and the effect of external pressure is negated by the action between the liquids.

Growing community of inventors

Gyeongbuk, South Korea

Jun Kyu Choi