Samsung Electronics Co., Ltd.

Jun-hong Min

Joon-Ho Kim

Kyu-youn Hwang

Hun-joo Lee

Chang-eun Yoo

Hee-kyun Lim

In-Ho Lee

Jang-seok Ma

Ki-Eun Kim

Soo-min Ma

Bong-jin Moon

Chang-Eun Yoo

Kwang-Ho Cheong

Young-Rok Kim

Ki-Woong Han

Provided is a method of isolating and purifying nucleic acids using an immobilized hydrogel or polyethylene glycol (PEG)-hydrogel copolymer. The method includes: immobilizing a functional group-containing hydrogel or PEG-hydrogel copolymer on a substrate; adding a mixed sample solution containing a salt and nucleic acids to the hydrogel- or PEG-hydrogel copolymer-immobilized substrate to bind the nucleic acids to the hydrogel or the PEG-hydrogel copolymer; washing the nucleic acid-bound hydrogel or PEG-hydrogel copolymer; and eluting the nucleic acids from the hydrogel or the PEG-hydrogel copolymer using an elution solvent. Therefore, binding and elution of nucleic acids can be performed even with no addition of a separate chemical substance, and an effect on a subsequent process such as PCR can be minimized. Furthermore, the amount and intensity for binding nucleic acids can be adjusted according to PEG concentration, and the presence of a hydrogel compound on a substrate enables patterning.

Method of isolating and purifying nucleic acids using immobilized hydrogel or PEG-hydrogel copolymer

A compound represented by formula (4), a substrate coated with the compound, a method of producing a microarray using the compound, and a microarray produced by the method are provided.

Linker compound, substrate coated with the compound, method of producing microarray using the compound and microarray produced by the method

Provided are a microfluidic device including an electrolysis device for cell lysis which includes an anode chamber, a cathode chamber and a separator, in which the separator is installed between the anode chamber and the cathode chamber, the anode chamber includes an inlet and an outlet for an anode chamber solution and an electrode, and the cathode chamber includes an inlet and an outlet for a cathode chamber solution and an electrode, and a method of electrochemically lysing cells using the same.

Microfluidic device comprising electrolysis device for cell lysis and method for electrochemically lysing cells using the same

Growing community of inventors

Gyeonggi-do, South Korea

Jun-hong Min