Chisso Corporation

Chisso Petrochemical Corporation

Jnc Corporation

Jun Hiraki

Hiroshi Morita

Masahiro Fujii

Masakazu Hatakeyama

Eriko Suzuki

Naoyuki Yoshida

Shigeyuki Aoyama

Yasuo Matsumoto

Kazushi Ishida

Shuji Sasaki

Takafumi Ito

Sumiko Watanabe

Masamichi Muto

Toru Shinto

Keiko Katsuta

Yuichi Yamamoto

Takuo Ikeda

The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like and which are excellent in a hydrolytic resistance, and dermatitis therapeutic agents and cosmetics using the same.

Compound selected from sulfated cellulose and salts thereof and dermatitis therapeutic agent

The present invention provides &#x3b5;-polylysine represented by formula (1), having a polyorganosiloxane group introduced into the molecule, and a process for production of the &#x3b5;-polylysine, in which the formula (1) is defined in the specification. The invention further provides an antimicrobial agent comprising an amino group-containing antimicrobial polymer having a polyorganosiloxane group introduced into the molecule, and an antimicrobial resin composition comprising an antimicrobial agent above and a resin.

Silicone-modified antimicrobial polymer, antimicrobial agent and antimicrobial resin composition

The incorporation of &egr;-polylysine or salt thereof (&egr;PL) having a water content of not more than 15% by weight in a resin composition makes it possible to obtain an antibacterial resin composition excellent in antibacterial capacity and safe in use. Since the &egr;PL can be fairly dispersed in the resin, the resulting molded article is not liable to destruction of external appearance. Accordingly, the antibacterial resin composition of the present invention can find good and wide application in medical sanitary goods, tableware, daily necessaries, automobile interior material, household appliance, film, sheet, fiber, coating compound such as paint, ink, and other goods which must be antibacterial. Further, the molded articles obtained from the resin composition according to the present invention can maintain its antibacterial effect even after repeated use and thus can be used over an extended period of time.

Antimicrobial resin composition and antimicrobial resin molded article comprising same

An effective process for producing .epsilon.-poly-L-lysine is provided, which process comprises cultivating a microorganism having .epsilon.-poly-L-lysine productivity, such as a bacterium belonging to the Streptomyces genus, in the form of immobilized bacterial cells under aerobic conditions, and according to which process, the bacterial cells cause no bacteriolysis; the immobilized bacterial cells retaining .epsilon.-poly-L-lysine productivity can be easily separated and recovered from the culture solution containing .epsilon.-poly-L-lysine; and semi-continuous or continuous production of .epsilon.-poly-L-lysine by the use of the immobilized bacterial cells is possible.

Process for producing .epsilon.-poly-L-lysine with immobilized

An antibacterial article inhibits the proliferation of microorganisms on the surface of food. The antibacterial article includes a substrate, such as a nonwoven material, on which is adsorbed .epsilon.-polylysine. The article is produced by applying an aqueous or alcoholic solution of .epsilon.-polylysine to the substrate by spraying or immersion.

Antibacterial articles and methods of producing the articles

An enzyme reaction stabilizer consisting of poly-L-lysine or its salt as an effective constituent, a method for using the enzyme reaction stabilizer, and an enzyme preservative consisting of poly-L-lysine or its salt as an effective constituent are disclosed in this invention. While enzyme reactions are carried out, the enzyme reaction stabilizer and the method for using it prevents both the deactivation of enzymes due to the proliferation of included microorganisms and the decomposition of the reaction products and there is an advantage in that the enzyme reaction stabilizer can easily be separated from the reaction products. On the other hand, while the enzyme solution is preserved, the enzyme preservative of this invention prevents the deactivation of the enzyme due to the proliferation of included microorganisms in the enzyme solution or the enzyme preserving solution. Even though the enzyme solution or the enzyme preserving solution may be supplied to the enzyme reactions, the enzyme reactions are not inhibited at all. The enzyme preservative of the present invention can easily be separated and removed from the reaction products.

Enzyme stabilization with poly-L-lysine

The present invention provides variant strains mass-producing .epsilon.PL which are obtained by variant treatment of a strain producing .epsilon.PL. For using the variant strains, the strains are cultured in a cultivated medium, .epsilon.PL is mass-produced and stored in the culture solution, and the stored .epsilon.PL is collected from the solution. For producing .epsilon.PL, a strain which produces .epsilon.PL is variant-treated, the obtained variant strain is cultivated in a culture medium to which L-lysine or L-lysine and one or more sugars are added, .epsilon.PL is mass-produced and stored in the culture solution, and the stored .epsilon.PL is collected from the solution. The variant strains producing .epsilon.PL in large quantities are preferably the strains which have tolerance to an analogue of L-lysine of Streptomyces albulus subsp. lysinopolymerus No. 346-D strain and plasmid-amplifiable variant strains of the same bacteria.

Method for producing .epsilon.-poly-L-lysine

The present invention provides mutants mass-producing .epsilon.PL which are obtained by mutation treatment of a strain producing .epsilon.PL. For using the mutants, the mutants are cultured in a cultivated medium, .epsilon.PL is mass-produced and stored in the culture solution, and the stored .epsilon.PL is collected from the solution. For producing .epsilon.PL, a strain which produces .epsilon.PL is mutation-treated, the obtained mutant is cultivated in a culture medium to which L-lysine or L-lysine and one or more sugars are added, .epsilon.PL is mass-produced and stored in the culture solution, and the stored .epsilon.PL is collected from the solution. The mutants producing .epsilon.PL in large quantities are preferably the mutants which have tolerance to an analogue of L-lysine of Streptomyces albulus subsp. lysinopolymerus No. 346-D strain and chloramphenicol-treated mutant of the same bacteria.

Strain mass-producing .epsilon.-poly-L-lysine

A whey protein gel which is transparent, thermostable, usable as food and is highly safe without damaging the nutritive value of whey protein, and a process for producing the gel are provided,

Whey protein gel and a process for producing the same

The invention provides cosmetics using a freeze-dried material which is obtained by freeze-drying an aqueous solution. The solution contains hyaluronic acid or sodium hyaluronate and magnesium-L-ascrbil phosphate.

Skin cosmetics

Ethanol preparations exhibiting a superior effect upon food preservation and also a superior antiseptic effect upon yeasts are provided, which preparations comprise a polylysine or a polylysine salt added to anhydrous ethanol or a water-containing ethanol in an ethanol concentration of 30% by weight or higher.

Method for treating food to control the growth of yeasts

Agent for preventing plant virus diseases such as tobacco mosaic viruses, potato viruses, cucumber mosaic viruses, etc. of this invention is obtained from a new agent containing polylysine as an active component. Polylysine can be used .alpha.-polylysine or .beta.-polylysine.

Growing community of inventors

Yokohama, Japan

Jun Hiraki