Jiangsu Hengrui Medicine Company Ltd.

Shanghai Hengrui Pharmaceutical Co., Ltd.

Other

Semiconductor Manufacturing International (Shanghai) Corporation

Semiconductor Manufacturing International (Beijing) Corporation

Hohai University

Shanghai Quicktron Intelligent Technology Co., Ltd

Jun Feng

Qiyun Shao

Feng He

Zhenxing Du

Jie Wang

Yahui Ma

Weidong Lu

Haoyu Zhang

Wei Zhang

Chao Xu

Guaili Wu

Yun Lu

Chao Wang

Lin Wang

Long Han

Zheng Hao Gan

Li Guo

Zhixian Tang

Zhonghua Zhu

Xianyue Zha

Bingshuai Du

Xiao Xu

Yuelong Zhu

Shijin Li

Dingsheng Wan

Jingquan Ye

Xiaoli Cao

Guohui Li

Qi Wu

The present disclosure relates to a crystal form of a pyridopyrimidine derivative and a preparation method thereof, and specifically relates to the crystal form of the compound of formula (I) and a preparation method thereof. The new crystal form has good physical and chemical properties, thereby facilitating clinical treatments.

Crystal form of pyridopyrimidine derivative and preparation method thereof

This invention shows a type of dual-sensing basin faucet, includes the shell of faucet, the shell of this faucet is setting a valve seat with adjustment switch. The top of valve seat is connected to the cavity of water outlet and cavity of solenoid valve. There is the outlet tube inside the cavity of water outlet and a solenoid valve inside the cavity of solenoid valve. Both outlet tube and solenoid valve are setting inside the shell of this faucet. There is circuit board setting on the top of outlet tube, and the circuit board is electrically connected with the solenoid valve. There is a support plate that is setting above the circuit board and is firmly connected with the circuit board.

One type of dual-sensing basin faucet

Disclosed is a method for preparing a benzofuran derivative. In particular, provided is a method for preparing a benzofuran derivative, wherein according to the method provided, reaction steps required to synthesize the benzofuran substance in the prior art can be effectively shortened.

Method for preparing benzofuran derivative

The present invention relates to crystal forms of an oxypyridine amide derivative and a preparation method therefor. In particular, the present invention relates to crystal forms A, B, C, D, E and F of a compound represented by formula (I) and a preparation method therefor. The crystal forms of the compound represented by formula (I) as described in the present invention have good crystal form stability and may be better for clinical use.

Crystal forms of oxypyridine amide derivative and preparation method therefor

A salt of a phenylpropionamide derivative and a preparation method therefor is described. Specifically, the salt of the compound of formula (I) has good stability, and can be better used in clinical treatment. The process for preparing the salt of the compound of formula (I) of the present invention is simple and easy to operate. 

Salt of phenylpropionamide derivative and preparation method therefor

A pharmaceutically acceptable salt as a renal outer medullary potassium channel (ROMK) inhibitor, specifically an L-tartrate and a crystal form I and crystal form II thereof, is described. The pharmaceutically acceptable salt of the ROMK inhibitor, specifically the L-tartrate, has improved bioavailability and stability.

Pharmaceutically acceptable salt as renal outer medullary potassium channel inhibitor

A traffic data stream aggregate query method and system includes the steps of acquiring spatial-temporal information of a mobile object to generate a traffic data stream, dividing data space into cells, grouping adjacent cells with similar frequency into few buckets, calculating Kalman gains of the buckets based on frequencies of the buckets, and indexing the buckets using a binary partition tree to form a BPT index of the current timestamp, and serializing the BPT after the end of the current timestamp to form a historical index; and performing aggregate query, wherein an optimum estimation value of the bucket frequency is utilized to replace for calculating when the frequency of the bucket changes a lot. The system includes: an information collection module, a data processing module, an index processing module, an application service module and an index storage module.

Traffic data stream aggregate query method and system

An electrostatic discharge (ESD) protection device includes a substrate including a device region and an ESD protection structure formed on the substrate in the device region. The device region includes a center region and edge regions separated by the center region, while the ESD protection structure includes a plurality of gate structures. The ESD protection device also includes a dielectric layer formed to cover the plurality of gate structures and a plurality of heat dissipation structures formed on the dielectric layer with each heat dissipation structure aligned with a corresponding gate structure along a direction perpendicular to a surface of the substrate. The area size of each heat dissipation structure aligned with a corresponding gate structure in the center region is larger than the area size of each heat dissipation structure aligned with a corresponding gate structure in the edge region.

Electrostatic discharge protection device and fabrication method thereof

Growing community of inventors

Shanghai, China

Jun Feng