Nissan Chemical Industries Limited

Jun Egi

Yuichi Hirai

Michiaki Adachi

Noriko Saito

Yusuke Shintani

Hiroshi Nagai

Takeshi Kawazu

Megumi Ueno

Koichi Yasutake

Daiki Takahashi

Yusuke Inaba

There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: where each substituent is defined in detail in the description or claims, for example Ris H or Calkoxy, etc., each of Land Lis independently a single bond or NR, etc., Lis Calkylene, etc., A is Caryl or 5 to 10-membered heteroaryl which is optionally substituted, etc., B is Ccycloalkylene, etc., D is Caryl or 5 to 10-membered heteroaryl which is optionally substituted, etc.

Triazinone compound and T-type calcium channel inhibitor

Growing community of inventors

Funabashi, Japan

Jun Egi