Mayo Foundation for Medical Education and Research

Jun Chen

Richard L Ehman

Phillip J Rossman

Kiaran P McGee

Kevin J Glaser

Stephen M Ansell

Yogesh K Mariappan

Bogdan Dzyubak

David A Woodrum

A phantom for magnetic resonance elastography (MRE) is provided. In particular, systems and methods for a phantom that is capable of generating a wave-like pattern in MRE images where a wavelength of the generated wave-like pattern is controlled by the phantom geometry. The geometrically controlled wavelength enables the phantom to calibrate MRE image acquisition and mechanical property calculation.

Systems and methods for a magnetic resonance elastography phantom

An acoustic driver system for use in applying an oscillating stress to a subject undergoing a magnetic resonance elastography (MRE) examination includes a flexible passive driver located in the bore of the magnet and in contact with the subject. A remotely located active driver is acoustically coupled to the passive driver and produces acoustic energy in response to an applied current. The passive driver produces shear waves in response to the acoustic energy and are directed into the body of the subject undergoing the MRE examination.

Passive acoustic driver for magnetic resonance elastography

A system and method for determining a response of a tumor following a chemotherapy process includes the use of a magnetic resonance elastography (MRE) driver and a magnetic resonance imaging (MRI) system. The method includes controlling the MRE driver and the MRI system to acquire raw MRE data from the tumor, inverting the raw MRE data to produce an elastogram of the tumor, and determining a response of the tumor to the chemotherapy process from the elastogram.

System and method for assessing response to chemotherapy using magnetic resonance elastography

A system and method for performing a magnetic resonance elastography (MRE) procedure using an MRI system to monitor operation of a medical device performing a medical procedure. The driver system includes a housing, a port located in the housing and connected to a driving power, and an inertial driver moved within the housing by the driving power. A passage is formed in the housing and extends from a first opening in the housing, through the inertial driver, and to a second opening in the housing. The inertial driver receives a medical device extending through the passage and engages the medical device to impart oscillatory motion thereto as the inertial driver is moved by the driving power. The imparted oscillatory motion travels along the medical device as a waveguide to deliver the oscillatory motion to tissue receiving the medical procedure to perform the MRE procedure.

System and method for inertial magnetic resonance elastography driver for use with interventional medical device

A flexible passive acoustic driver for use in an acoustic driver system which applies an oscillating stress to a subject undergoing a magnetic resonance elastography (MRE) examination which includes receiving acoustic pressure waves from an active driver through a tube and imparts pressure waves to a subject of an imaging procedure. In one configuration, the passive driver includes a flexible bag that forms the walls of an acoustic cavity, and a structure filling material located inside the acoustic cavity provides support for the flexible bag. The flexible bag conforms to the shape of the subject and may be held in place by an elastic band. The passive driver can have an integrated or detachable non-active push-on compartment which is rigid or semi-flexible to improve the human-driver mechanical coupling and the driver energy efficiency of converting acoustic pressure to mechanical vibration applied to a subject.

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Rochester, MN, United States of America

Jun Chen