Abbvie Inc.

Jun Chen

Michael E Kort

Richard J Perner

Stanley DiDomenico

Anil Vasudevan

Philip R Kym

Arthur Gomtsyan

Jerome F Daanen

Erol K Bayburt

Robert G Schmidt

Eric A Voight

Heath A McDonald

Compounds of formula (I) wherein R, R, R, and Y are defined in the description are TRPA1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

TRPA1 antagonists

Compounds of formula (I) wherein R, R, R, m, and Y are defined in the specification are TRPA1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Disclosed herein are compounds of formula (I), or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R, R, R, R, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

TRPV1 antagonists

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R, R, R, R, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

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Lake Bluff, IL, United States of America

Jun Chen