Bangor University

Diagnostig Ltd.

Juma'a Raheem Najeem Al Dulayymi

Mark Stephen Baird

Christopher David Gwenin

Johan Adriaan Marc Grooten

Seppe Vander Beken

Salam Ghafour Taher

Maximilliano Maza-Inglesias

A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is a mycolic acid wax ester derived antigen.

Compositions and methods

A method of preparing a compound of formula (III):(M)-(S)-(M')&#x2003;&#x2003;(III)wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M&#x2032; is independently a mycolic acid residue including a &#x3b2;-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each &#x3b2;-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.

Methods for pathogen detection and disease treatment

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Bangor, United Kingdom

Juma'a Raheem Najeem Al Dulayymi