Edwards Lifesciences Cardiaq LLC

Edwards Lifesciences Corporation

Julio Cesar Sanchez

Glen Thomas Rabito

Alexander H Cooper

J Brent Ratz

David Robert Landon

Kevin M Stewart

Arshad Quadri

Patrick Chow

Luca Pesce

Garrett Dallas Johnson

Hieu Minh Luong

Yen Liao

Tarannum Ishaq Gutierrez

Taylor Jacob Scheinblum

Ramon Aguilar, Jr

Jesse Robert Edwards

Siddharth Vad

Lindsay Lam

Hiroshi Okabe

Brent J Ratz

Glen T Rabito

Matthew A Peterson

Kevin M Golemo

Victoria Cheng-Tan Wu

Lisong Ai

Juliet Laura Schwartz

Wendy Vo Pham

Ramon Aguilar

Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. A delivery component can have a plurality of slots that provide for desired bending of the delivery component, particularly compound bending of the delivery component that can facilitate steering of the delivery component in three dimensions.

Steerable delivery system for replacement mitral valve and methods of use

Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.

Steerable rail delivery system

Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components, including a flexible nose cone, multi-layer sheath, and pre-compressed shaft, which can be moveable relative to each other.

Replacement mitral valve, delivery system for replacement mitral valve and methods of use

Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. Disclosed are a number of features that can improve steerability or release of the prosthesis into the body location.

Steerable delivery system and components

A mitral valve prosthesis includes an hourglass shaped inner frame and a bulbous outer frame. A valve body having a plurality of leaflets is positioned within an interior region of the inner frame. The leaflets are shaped to substantially conform to an interior surface of the inner frame when the leaflets are in an open position. As a result, the gap between the leaflets and the inner frame is decreased, thereby reducing the likelihood of thrombus formation. Ventricular anchors are preferably provided along a distal end of the inner frame. The anchors extend proximally for placement behind native mitral valve leaflets. A fabric skirt may extend along an inner or outer surface of the outer frame. In preferred embodiments, the fabric skirt extends distally beyond a distal end of the outer frame and is adapted for forming a seal along the mitral valve annulus.

Prosthetic mitral valve with improved anchors and seal

Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery devices for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components which are moveable relative to each other. The delivery system can include a nose cone which can cover at least a first end of the prosthesis, an outer elongate member which can cover at least a second end of the prosthesis, and a tether which can at least partially restrain the prosthesis from deployment.

Prosthesis, delivery device and methods of use

Disclosed herein are embodiments of a prosthesis and delivery device, as well as methods of use. The delivery device can be composed of an inner retention assembly configured to carry an expandable prosthesis to an in situ target location. The inner retention assembly can slide within an outer elongate hollow member which can cover the expandable prosthesis. The outer elongate hollow member can further be longitudinally collapsed into a receiving member located at the distal end of the outer elongate hollow member.

Growing community of inventors

Garden Grove, CA, United States of America

Julio Cesar Sanchez