Sofradim Production

Julien Claret

Sébastien Ladet

Sebastien Francois

Maud Buffin

Sébastien Francois

Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.

Implant for tissue repair including chitosan

Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: &#x2014;a) a chitosan solution is prepared, &#x2014;b) said solution is poured into a mold in order to form a layer, &#x2014;c) the layer obtained in b) is lyophilized so as to obtain a porous layer, &#x2014;d) said porous layer obtained in c) is compressed, &#x2014;e) the compressed porous layer obtained in d) is neutralized by means of an NHOH solution. It also relates to an implant comprising a layer obtained according to such a method.

Method for preparing a chitosan-based porous layer

Mono- and multi- layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.

The present disclosure provides mono- and multi-layered implants which include at least one porous layer made from a freeze-dried aqueous solution containing chitosan, the solution having a pH of less than about 5.

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Villefranche-sur-Saône, France

Julien Claret