Eli Lilly and Company

Juliana Maude Bue-Valleskey

Charles David Jones

Jill A Panetta

David C Hunden

Walter N Shaw

Mark Louis Heiman

Thomas Wesley Stephens

Frank C Tinsley

This invention describes methods of treating conditions associated with an excess of neuropeptide Y which comprises administering an analog of an obesity protein. This invention further describes methods of treating conditions associated with an excess of neuropeptide Y which coomprises administering an analog of an obesity protein in combination with a neuropeptide Y antagonist. This invention demonstrates that the obesity protein acts by reducing the production of neuropeptide Y by the hypothalamus.

Methods of treating neuropeptide Y-associated conditions

This invention describes methods of treating conditions associated with an excess of neuropeptide Y which comprises administering an obesity protein. This invention also describes methods of treating conditions associated with an excess of neuropeptide Y which comprises administering an obesity protein in combination with a neuropeptide Y antagonist. This invention demonstrates that the obesity protein acts by reducing the production of neuropeptide Y by the hypothalamus.

Methods of treating nueropeptide Y-associated conditions

Provided are methods for treating hyperglycemia and Alzheimer's disease utilizing certain rhodanine derivatives. Certain of the rhodanine derivatives utilized in the instant methods are novel and, accordingly, such compounds and pharmaceutical formulations thereof are also provided.

Compounds useful as hypoglycemic agents and for treating Alzheimer's

Provided is a method for treating hyperglycemia utilizing certain rhodanine derivatives. Certain of the rhodanine derivatives utilized in the instant method are novel and, accordingly, such compounds and pharmaceutical formulations thereof, are also provided.

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Indianapolis, IN, United States of America

Juliana Maude Bue-Valleskey