Humacyte, Inc

Other

Juliana Blum

Laura E Niklason

Justin T Strader

William E Tente

Shannon Dahl

Joseph J Lundquist

Shannon L M Dahl

Heather L Prichard

Parrish M Galliher

Colin R Tuohey

Michael Edward Fisher

Patrick M Guertin

Joseph D Crowell

Yuling Li

Geoffrey Erickson

Frank Zeigler

Shannon Lm Dahl

Shannon LM Dahl

The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

Tubular tissue-engineered constructs

Tissue-engineered constructs

A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions.

Tissue and organ graft bioreactor and method of operation

The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.

Compositions and methods for soft tissue augmentation

Growing community of inventors

Wake Forest, NC, United States of America

Juliana Blum