Ethicon, Gmbh

Closure Medical Corporation

Julian A Quintero

Jerry Y Jonn

Leo B Kriksunov

Glenn Hoskin

Daniel L Hedgpeth

Robert J Tannhauser

William M Cotter

John S Bobo

Jack Goodman

Jeffrey G Clark

Timothy P Hickey

Shane A Lacy

Jon Moseley

Kevin Shaun Weadock

Jianxin Guo

Ibraheem T Badejo

Keith R D'Alessio

Upvan Narang

Michael F Brady

Robert Anthony Rousseau

Duan Li Ou

Roy Keller Thompson

Jon Pope Moseley

J Christopher Marmo

Glenn R Cook

Joe B Barefoot

Lawrence H Mainwaring

Elena Wolfe

Wendy Y Su

Amitha Anand Kumar

Chin Park

Frank S Leparik

Scott Marc Cannizaro

Michelle Knotts

Keith A Pinto

John Bobo

Dennis D Burns

A system or device for skin closure comprises an elastic flat flexible tape elongated along a longitudinal axis and having a lower side and an opposing upper side, said tape having a pressure sensitive adhesive on at least a portion of the lower side, said tape having a plurality of openings arranged side-by-side with spaces between said openings oriented across the longitudinal axis.

Skin closure systems and devices of improved flexibility and stretchability for bendable joints

A surgical incision drape, comprises a flexible substantially flat areal substrate having an upper side and an opposing tissue-facing side, having a longitudinal axis and a pressure sensitive adhesive disposed on the tissue-facing side; at least one hollow microtubular compartment containing a flowable medical agent, said hollow microtubular compartment positioned to intersect the longitudinal axis and embedded into the substrate or positioned on the substrate.

Wound closure systems for reducing surgical site infections comprising incision drapes filled with releasable antimicrobial agents

A wound closure device and a method of its use are disclosed. The wound closure device includes a wound closure strip, the wound closure strip including a wound-facing side and a top side, the wound-facing side comprises an adhesive applied over at least a portion of the wound facing side of the wound closure strip and a non-symmetric, two-part release liner assembly detachably adhered to the adhesive, the release liner assembly including a first section and a second section with the second section including a wound closure strip-free portion forming a tab. In an alternate embodiment, the device is multi-segmented and the wound closure strip may be coextensive with the release liner assembly.

Methods and devices for skin closure

Novel compositions and systems for closure of wounds are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

Anisotropic wound closure systems

Release paper for wound treatment devices

A device for application onto wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, comprising a thin flexible flat porous tape, preferably a mesh, elongated along a longitudinal axis and having a lower side or wound-facing side and an opposing upper side, a periphery, and central portion in immediate vicinity of the axis; said tape coated or impregnated with an initiator or accelerator of polymerization; said tape having a plurality of elongated traces of soluble pressure sensitive adhesive (PSA) disposed on the wound-facing side; said traces covering from about 3% to about 50% of area of said tape and extending from the periphery to the central portion of said tape.

Skin closure devices with self-forming exudate drainage channels

A method of joining together two tissue layers includes positioning a tissue anchor over a first tissue layer. The tissue anchor includes a plate having top and bottom surfaces, an array of first pins projecting from the bottom surface of the plate that oppose the first tissue layer, and an array of second pins projecting from the top surface of the plate that face away from the first tissue layer. A second tissue layer is placed over the first tissue layer and the tissue anchor so that the second pins oppose the second tissue layer. The second tissue layer is pressed onto the tissue anchor and toward the first tissue layer so that the first pins advance into the first tissue layer and the second pins advance into the second tissue layer for joining together the first and second tissue layers. The plate has second pin apertures and the second pins are free to slide and move independently of one another within the second pin apertures.

Methods of using tissue anchors having bi-directional arrays of barbed pins for joining together parallel tissue layers

An article, such as a tissue bonding article, includes a flexible material, a polymerization initiator or rate modifier disposed in or on the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material, where the polymerization initiator or rate modifier is a polymerization initiator or rate modifier for the polymerizable adhesive composition.

Adhesive-containing wound closure device and method

A tissue bonding article includes a flexible material, an adhesive substance applied over at least a portion of a bottom side of the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material.

A system for testing substrates includes a first elongated member including an outer end, an inner end, an outer surface that extends between the outer and inner ends, and a concave surface at the inner end, and a second elongated member including an outer end, an inner end, an outer surface that extends between the outer and inner ends of the second elongated member, and a convex surface at the inner end of the second elongated member that opposes the concave surface at the inner end of the first elongated member. A joint interconnects the first and second elongated members for guiding sliding movement of the concave surface of the first elongated member over the convex surface of the second elongated member between extended and flexed positions. A first clamping assembly is coupled with the first elongated member and at least one first clamping assembly spring normally urges the first clamping assembly away from the inner end of the first elongated member. A second clamping assembly is coupled with the second elongated member and at least one second clamping assembly spring normally urges the second clamping assembly away from the inner end of the second elongated member. A substrate overlying the outer surfaces of the first and second elongated members has a first end secured to the first clamping assembly and a second end secured to the second clamping assembly.

Systems, devices and methods for testing substrates to evaluate wound closure products

A device for application onto incisions or wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, having a flat porous mesh elongated along a longitudinal axis and having an upper side and an opposing lower or wound facing side and a central portion in immediate vicinity of the axis; further having a plurality of pores and windows in said mesh, said windows substantially larger than said pores and arranged along said longitudinal axis in said central portion; a crosslinking or polymerization accelerator or initiator disposed in or on the mesh; and a pressure sensitive adhesive disposed on at least a portion of the lower surface of the mesh.

Skin closure devices with interrupted closure

A method of reinforcing subcutaneous fragile tissue includes obtaining an absorbable surgical mesh having top and bottom major surfaces, the absorbable surgical mesh including a stitching zone and first and second reinforcing zones that bound opposite sides of the stitching zone. The method includes making an incision in a patient's skin for exposing subcutaneous fragile tissue, using one or more absorbable adhesives for adhering the bottom major surface of the absorbable surgical mesh to the subcutaneous fragile tissue, creating an incision through the stitching zone of the absorbable surgical mesh and into the subcutaneous fragile tissue, performing a surgical procedure through the incision, and passing an absorbable suture through the stitching zone of the absorbable surgical mesh and the fragile tissue for closing the incision.

Systems and methods for closing incisions formed in fragile tissue

A scaffold for joining two layers of tissue, comprises a substantially flat and flexible body having a top surface, a bottom surface and sidewalls; at least one channel within the body starting at an injection port; a plurality of first passages on the top surface and a plurality of second passages on the bottom surface, said passages in fluid communication with the channel; a plurality of third passages penetrating the body from the top surface to the bottom surface, said plurality of third passages not in fluid communication with the channel.

Scaffolds with channels for joining layers of tissue at discrete points

Growing community of inventors

Raleigh, NC, United States of America

Julian A Quintero