Eth Zurich

University of California

The University of North Carolina at Chapel Hill

Virginia Tech Intellectual Properties Inc

Cytosurge Ag

Julia Vorholt-Zambelli

Michael Gabi

Pascal Behr

Janos Voeroes

Stefan Pablo Doerig

Philipp Stiefel

Thomaso Zambelli

Bingyu Zhao

Jiamin Miao

Maximilian Mittelviefhaus

Jeffrey L Dangl

Kunru Wang

Asaf Levy

The present invention provides for a composition comprising a purified or isolated Hyde1 gene product, or a functional fragment thereof; a modified host cell capable of expressing a Type VI secretion system (T6SS), Hyde1, and/or Hyde2, or a functional fragment thereof; a method of treating a disease caused all or in part by a bacterial cell, comprising administering a composition of the present invention to a subject in need thereof; and a method to limit or reduce growth of a pathogenic bacteria in an environment, comprising: introducing a non-pathogenic bacterial capable of expressing a Type VI secretion system (T6SS), Hyde1, and/or Hyde2, or functional fragment thereof, to an environment.

Methods and compositions useful for inhibiting growth of certain bacteria

The invention relates to a method for spatially manipulating a microscopic object including providing a cantilever () having a tip with an opening () and a microchannel () extending through the cantilever () in its longitudinal direction. A suspension means is provided for holding the cantilever () and spatially moving the cantilever along a predetermined spatial path. A pressurizing means is provided for applying a predetermined pressure to the microchannel () and the cantilever () is moved with its tip to the microscopic object to be spatially manipulated. At least a part of the microscopic object is picked up with said cantilever () by reducing the pressure within the microchannel () relative to the pressure outside the tip of the cantilever (). The microscopic object is then moved along a predetermined spatial path by means of the cantilever ().

Method for spatially manipulating a microscopic object and device for conducting said method

Growing community of inventors

Zurich, Switzerland

Julia Vorholt-Zambelli