The Secant Group, LLC

Julia Donnelly

Peter D Gabriele

Jeremy J Harris

Charles Brendan Nicholson

Carissa Smoot

Steven Lu

Brian Ginn

Kayla Wroblesky

Michael S Flemmens

Austin Robertson

A method of forming cured microparticles includes providing a poly(glycerol sebacate) resin in an uncured state. The method also includes forming the composition into a plurality of uncured microparticles and curing the uncured microparticles to form the plurality of cured microparticles. The uncured microparticles are free of a photo-induced crosslinker. A method of forming a scaffold includes providing microparticles including poly(glycerol sebacate) in a three-dimensional arrangement. The method also includes stimulating the microparticles in the three-dimensional arrangement to sinter the microparticles, thereby forming the scaffold having a plurality of pores. A scaffold is formed of a plurality of microparticles including a poly(glycerol sebacate) thermoset resin in a three-dimensional arrangement. The scaffold has a plurality of pores.

Cured biodegradable microparticles and scaffolds and methods of making and using the same

The application is directed to aqueous dispersible biodegradable compositions of esters which are the condensation reaction product of a polyol and a diacid which are within a matrix of hydrated polypeptide. The compositions are useful in additive manufacturing and other applications for use with implantable articles. In some embodiments, the ester in the compositions is the product of a glyercol-sebacic acid condensation reaction.

Composition, methods and devices useful for manufacturing of implantable articles

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Chalfont, PA, United States of America

Julia Donnelly