Mesoscale Technologies, Llc.

Jules VanDersarl

Cecilia Zimmerman

Sandor L Kovacs

Aaron H Leimkuehler

Jacob N Wohlstadter

Rodger Darin Osborne

Manish Kochar

Charles M Clinton

Gary I Krivoy

Leo Tabakin

Jon S Willoughby

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format. Also disclosed are systems, devices, and methods provided herein for using a CCD camera based system to generate measurements having reduced crosstalk between measurements of multiple spatially separated subjects. CCD camera based systems as provided herein use improved reference level clamping circuits configured to fully reset reference levels during CCD readout, thereby reducing a level of crosstalk between measurements.

Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between CCD measurements

Instrument

The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.

Device housing with lighting

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.

Assay apparatuses, methods, and reagents

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Gaithersburg, MD, United States of America

Jules VanDersarl