Aventis Cropscience S.a.

Entopharm Co., Ltd.

Jules Hoffman

Philippe Bulet

Sergey Ivanovich Chernysh

German Petrovich Bekker

Soo In Kim

Natalia Borisovna Makhaldiani

Georges L Freyssinet

Richard Derose

Mireille Lamberty

Gary Brookhart

The invention belongs to the field of biologically active peptides specifically stimulating antiviral, antimicrobial and antitumor activity of the human and animal immune system.

Alloferons&#x2014;immunomodulatory peptides

The invention concerns heliomicine, A DNA sequence coding for heliomicine, a vector containing it for transfroming a host organism and the transformation method. The invention concerns heliomicine as a medicine in particular for treating fungal infections. More particularly, it concerns the transformation of plant cells and plants, the heliomicine produced by the transformed plants ensuring their resistance to diseases, in particular diseases of fungal origin.

Gene coding for heliomicine and use thereof

Alloferons&mdash;immunomodulatory peptides

The invention concerns a chimeric gene containing a DNA sequence coding for drosomycin, a vector containing the chimeric gene, a method for transforming plants and the resulting transformed plants. The drosomycin produced by the plants provides them with resistance to diseases, in particular of fungal origin.

Chimeric gene encoding drosomycin, vector containing it and production of disease-resistant transgenic plants

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Strasbourg, France

Jules Hoffman