Delsitech Oy

Other

Bioxid Oy

Jukka Salonen

Antti Yli-Urpo

Manja Ahola

Eija Säilynoja

Harry Gosta Jalonen

Mika Koskinen

Veli-Matti Kähäri

Patricia Stoor

Risto Penttinen

Eva S&ouml;derling

Eva Soderling

Harry Jalonen

Ulla Tuominen

Eija Saeilynoja

Veli-Matti Kaehaeri

A biodegradable carrier is produced for preservation and/or controlled delivery of biologically active agents where said biodegradable carrier is a silica xerogel which is made from water and silane by using acid or base as a catalyst, and biologically active agents in said biodegradable carrier are infecting and/or transfecting viruses. Silica xerogel material can be pharmaceutically acceptable and it can be used as a medicine.

Biodegradable carrier and method for preparation thereof

A biodegradable carrier is produced for preservation and/or controlled delivery of biologically active agents where the biodegradable carrier is a silica xerogel which is made from water and silane by using acid or base as a catalyst, and biologically active agents in the biodegradable carrier are infecting and/or transfecting viruses. Silica xerogel material can be pharmaceutically acceptable and it can be used as a medicine.

A composition for controlled release of a biologically active agent from a carrier. The biologically active agent is heparin or a related biologically active acidic polysaccharide and the carrier is a sol-gel derived silica xerogel. The xerogel is derived from a tetraalkoxysilane such as tetrethoxysilane (TEOS) and part of the tetraalkoxysilane is replaced by an organomodified alkoxysilane, preferably an akylsubsitituted alkoxysilane. The invention also includes a method for the preparation of this composition.

Compositions for controlled release of a biologically active agent, and the preparation thereof

The invention relates to a method for reducing the viability of detrimental oral microorganisms in an individual, said method comprising subjecting the individual's oral cavity to a bioactive glass, the average particle size of which is less than 100 &mgr;m. Furthermore, this invention concerns a method for the prevention of dental caries and/or gingivitis in an individual, said caries being caused by a cariogenic bacteria; or for prevention or treatment of periapical infections. Further the invention relates to a method for the whitening and/or mechanical cleaning of an individual's teeth.

Method for reducing the viability of detrimental oral microorganisms in an individual, and for prevention and/or treatment of diseases caused by such microorganisms; and whitening and/or cleaning of an individual's teeth

The invention relates to a method for reducing the viability of detrimental oral microorganisms in an individual, said method comprising subjecting the individual's oral cavity to a bioactive glass, the average particle size of which is less than 100 &mgr;m. Furthermore, this invention concerns a method for the prevention of dental caries and/or gingivitis in an individual, said caries being caused by a cariogenic bacteria; or for prevention or treatment of periapical infections. Further the invention relates to a method for the whitening and/or mechanical cleaning of an individual'teeth.

Use of bioactive silicious glass and new compositions containing

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Turku, Finland

Jukka Salonen