Kissei Pharmaceutical Co., Ltd.

Juichi Fukuyama

Masayuki Yamada

Arao Ujiie

Shuichiro Hamano

Keiji Miyazawa

The present invention provides pharmaceutical compositions for the prevention or treatment of lipid metabolism disorders. The pharmaceutical compositions comprising, as an active ingredient, (2S)-2-benzl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic aid (generic name: mitiglinide) or a pharmaceutically acceptable salt thereof, or a hydrate thereof exert remarkable lipid metabolism improving effect, and are useful for, for example, hyperlipidemia such as hypertriglyceridemia of diabetic patients or the like.

Pharmaceutical composition for treatment of lipid metabolism disorder

A method for treating patients to inhibit restenosis associated with coronary intervention, which comprises administering compounds of the class of aminobenzoic acids, specifically 2-(3,4-dimethoxy-cinnamoyl)-aminobenzoic acid or its pharmaceutically acceptable salt at a dosage which is sufficient to maintain the plasma concentration at about 100.mu. molar for a period of time of less than three months.

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Tokyo, Japan

Juichi Fukuyama