Industrial Technology Research Institute

Jgc Corporation

Jui-Mei Lu

Yasuaki Ogawa

John Jianghann Lin

Naoki Tahara

Pei Kan

Yi-Fong Lin

Yuan-Hung Hsu

Chi-Heng Jian

Yuan-Chia Chang

Tomoya Yamashita

Min-Ying Lin

Felice Cheng

Shin-Jr Liu

Shuzo Kojima

Hsiang Fa Liang

Chu-Chun Hsueh

Yung Chu Chen

Ming-Thau Sheu

Ting Fan Yang

Li Wen Chang

Ae June Wang

Yo Wen Lo

Sung En Chen

Chiao Pin Li

Po Hong Lai

Chia-Wen Liu

Sung-En Chen

John Jiang Hann Lin

Sung En Cheng

An object of the present invention is to provide a method for producing a microcapsule formulation using a biodegradable polymer, the method being capable of avoiding direct contact of a peptidic physiologically active substance with an organic solvent layer, and achieving a high encapsulation efficiency of the peptidic physiologically active substance.

Microcapsule formulation and method for producing the same

A sustained release composition comprising a polymer and manufacturing method thereof. The sustained release composition comprises a polymer, a bioactive agent, and a release rate determined agent, wherein the release rate determined agent is dispersed in the sustained release composition to control the release rate of the bioactive agent. The method comprises providing an oil phase comprising a bioactive agent, a polymer, and a release rate determined agent; providing an aqueous phase comprising a surfactant; mixing the oil phase with the aqueous phase to form the sustained release composition having a controlled release effect.

Sustained release composition and manufacturing method thereof

This present disclosure relates to pharmaceutical compositions for treating tumors using a polymeric micelle encapsulating an anti-tumor drug. The polymeric micelle comprises block copolymers comprising at least one hydrophilic block, at least one hydrophobic block, and at least one zwitterion. The present disclosure also relates to methods of enhancing the solubility of such drugs, methods of increasing the blood circulating time of such drugs, and methods of delivering such drugs to one or more solid tumors.

Drug composition for treating tumor with polymeric micelle encapsulating anti-neoplastic

A delivery system. The delivery system includes a carrier having a surface, an active compound comprising small molecule compounds or peptides for use as an analgesic encapsulated into the carrier, and a glutathione or a glutathione derivative grafted on the surface of the carrier. The invention also provides a method of analgesia including conducting the active compound to a subject.

Glutathione-based delivery system

Growing community of inventors

Hsinchu County, Taiwan

Jui-Mei Lu