Miltenyi Biotec B.v. Co., Kg

Miltenyi Biotec, Gmbh

Miltenyi Biotec B.v. & Co. Kg

Juergen Schulz

Winfried Schimmelpfennig

Holger Lantow

Stefan Miltenyi

Martin Biehl

Eiad Kabaha

Niklas Elmar Neuschaefer

Elmar Niklas Neuschaefer

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder, a pump and a plurality of valves configured to at least partially control fluid flow through a fluid circuitry and a separation column positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

Method for manufacturing a patient specific cell population using a multifunctional self-contained apparatus and tubing set

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (), a pump () and a plurality of valves (-) configured to at least partially control fluid flow through a fluid circuitry and a separation column () positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

Devices and disposables for patient-specific cell therapy manufacturing

Single use tubing set for making genetically modified donor cells for reinfusion into a patient

Device and procedure for producing a cellular pharmaceutical product enriched in genetically modified target cells at the bedside or in a surgical room

Equipment and procedure for culturing, separating, and genetically modifying donor cells for reinfusion into a patient

Preparing genetically modified cells using a device that is configured for sterile processing of cells at the bedside or in a surgical room

Preparing antigen-specific T cells using a self-enclosed processing system that contains both a centrifuge and a magnetic separation column

Self-contained disposable tubing set for sterile preparation of cells by culturing, centrifugation, and column chromatography

System for separating a cell sample by centrifugation and column chromatography while maintaining sterility

The presently disclosed subject matter proposes an apparatus () and a method for transferring energy and/or a substance from a non-rotating component of an apparatus to a rotating device ()&#x2014;or vice versa&#x2014;through an intermediary component ('). In one configuration, the intermediary component (&#x2032;) is a symmetrically arranged pair of tubes, useful in centrifugal separation, and which is subject to continuous rotation while tube ends are fixed in a lower, stationary range or stand still.

Apparatus and method for transferring energy and/or a substance to rotating means

Growing community of inventors

Jesteburg, Germany

Juergen Schulz