Nmi Naturwissenschaftliches Und Medizinisches Institut an Der Universitaet Tuebingen

Tetec Tissue Engineering Technologies

Tetec Tissue Engineering Technologies Ag

Nmi Naturwissenschaftliches Und Medizinisches Institut an Der Universitat Tubingen

Juergen Mollenhauer

Christoph Gaissmaier

Helmut Wurst

Karin Benz

Burkhard Schlosshauer

Reinout Stoop

Barbara Platz

Beate Scholz

The invention relates to an injectable biocompatible composition based on a polymeric support as well as to a method for producing it, which composition which comprises at least one hydrophilic polymer, wherein the polymer is polymerizable in situ to form a gel, and wherein the hydrophilic polymer is crosslinkable serum albumin or crosslinkable serum protein. The composition can be used in the restoration, the reconstruction, and/or the replacement of tissues and/or organs, or as a drug release implant in mammals. The composition is particularly suitable for treating cartilage disorders of a diseased or injured articular site in a mammal.

Injectable biocompatible composition

A method of determining identity, purity and/or potency of chondrocytes in vitro includes a) isolating and, optionally, culturing chondrocytes from a biological sample, and b) determining gene expression of at least one marker in the chondrocytes selected from the group consisting of FLT-1, IL-1beta, BSP-2, and type I collagen.

Methods of determining chondrocytes

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Reutlingen, Germany

Juergen Mollenhauer