Old Dominion University Research Foundation

Other

Old Dominion Research Foundation

Juergen Friedrich Kolb

Karl H Schoenbach

Robert Chiavarini

Robert O Price

Tammo Heeren

Shu Xiao

Roelof Trip

Andrei G Pakhomov

Stephen J Beebe

Stephen P Beebe

Richard Blomgren

Abdel-Aleam Hefney Mohamed

Aron Stubbins

Abdel-Aleam H Mohamed

Ravindra Joshi

Gary C Schafran

An instrumentfor delivering a high voltage pulse to tissue is disclosed. The instrumentcan include an outer support memberwith a liquid reservoirthat has a liquid-contacting interior surface, an openingat a distal endof the outer support member, and a ground electrodeextending in a longitudinal direction and having a lower surfaceproximate the opening. The instrumentcan also include a working electrodeextending longitudinally from the liquid-contacting interior surfacewith a needle-shaped distal portionproximate the distal end; and an inlet portand an outlet portin liquid communication with the liquid reservoir. The working electrodecan be electrically isolated from the ground electrodeby an insulating portionof the outer support member, and a direct path can exist through the liquid reservoirbetween the ground electrodeand the working electrode

Medical instrument for delivery of high voltage pulses and method of delivering the same

A method and device for aggregating algae in an aqueous solution is disclosed. The method can include providing an algae feed comprising a liquid and algae dispersed therein. The algae feed can be aggregated by applying a nanosecond pulsed electric field to the algae feed. The nanosecond pulsed electric field can include a plurality of electric pulses having a pulse duration ranging from 1 to 1,000 nanoseconds. The method can also include separating an aggregated algae stream from the algae feed and feeding the aggregated algae stream to a lipid extraction operation.

System and method for high-voltage pulse assisted aggregation of algae

A medical instrument for delivering electrotherapy to tissue that includes an outer support member having a ground plate at a distal end of the outer support member, and a protrusive element having a tip that extends beyond the ground plate. A portion of the protrusive element proximate the ground plate can act as an electrical insulator and a portion of the protrusive element proximate the distal end of the protrusive element can include a first electrode. The protrusive element can be designed to penetrate into tissue below a tissue surface while a tissue contacting surface of the ground plate rests against the tissue surface. Also disclosed are systems incorporating the medical instrument and methods of electrotherapy to subsurface tissue using the medical instrument.

Delivery device, system, and method for delivering nanosecond pulsed electric fields

A microhollow cathode discharge assembly capable of generating a low temperature, atmospheric pressure plasma micro jet is disclosed. The microhollow assembly has two electrodes: an anode and a cathode separated by a dielectric. A microhollow gas passage is disposed through the three layers. In some embodiments, the passage is tapered such that the area at the first electrode is larger than the area at the second electrode. When a potential is placed across the electrodes and a gas is directed through the gas passage, then a low temperature micro plasma jet can be created at atmospheric pressure or above.

Method and device for creating a micro plasma jet

A microhollow cathode discharge assembly capable of generating a low temperature, atmospheric pressure plasma micro jet is disclosed. The microhollow assembly has at two electrodes: an anode and a cathode separated by a dielectric. A microhollow gas passage is disposed through the three layers, preferably in a taper such that the area at the anode is larger than the area at the cathode. When a potential is placed across the electrodes and a gas is directed through the gas passage into the anode and out the cathode, along the tapered direction, then a low temperature micro plasma jet can be created at atmospheric pressure. Selection of gas microhollow geometry and operational characteristics enable the application of the assembly to low temperature treatments, including the treatment of living tissue.

Cold air atmospheric pressure micro plasma jet application method and device

A system for producing maximal, but reversible bioeffects, for neuromuscular disruption. Methods for facilitation of neuromuscular functions in diseases and conditions of decreased excitability are provided.

Modulation of neuromuscular functions with ultrashort electrical pulses

A microhollow cathode discharge assembly capable of generating a low temperature, atmospheric pressure plasma micro jet is disclosed. The microhollow assembly has at two electrodes: an anode and a cathode separated by a dielectric. A microhollow gas passage is disposed through the three layers, preferably in a taper such that the area at the anode is larger than the area at the cathode. When a potential is placed across the electrodes and a gas is directed through the gas passage into the anode and out the cathode, along the tapered direction, then a low temperature micro plasma jet can be created at atmospheric pressure.

Growing community of inventors

Norfolk, VA, United States of America

Juergen Friedrich Kolb