Gruenenthal Gmbh

Basf Aktiengesellschaft

Juergen Betzing

Johannes Heinrich Bartholomaeus

Kurt H Bauer

An orally administered preparation with controlled lease of an opioid analgesic in the form of crystals having particle size of 10 &mgr;m to 3 mm, preferably of 50 &mgr;m to 1 mm, which have at least one controlled release coating.

Opioid analgesics with controlled active substance release

Solid medicinal forms having a multiphase structure for oral administration, containing gatifloxacin or pharmaceutically acceptable salts or hydrates thereof and auxiliary substances selected from the group of fillers, binders, lubricants, disintegration aids and mixtures thereof, in which the inner phase contains the active ingredient gatifloxacin or pharmaceutically acceptable salts or hydrates thereof and auxiliary substances from the group of binders, fillers, disintegration aids and mixtures thereof, and at least one outer phase necessarily contains at least one disintegration aid and further auxiliary substances from the group of at least one lubricant, optionally fillers and/or optionally binders, and a process for the preparation of such solid medicinal forms.

Oral medicinal preparations with reproducible release of the active ingredient gatifloxacin or its pharmaceutically suitable salts or hydrates

Rapidly disintegrating, binder-free tablets of tramadol or a tramadol salt for oral administration comprising microcrystalline cellulose and tramadol or a pharmaceutically acceptable tramadol salt in a weight ratio of at least 2:1.

Growing community of inventors

Aachen, Germany

Juergen Betzing